User:R. Jeremy Johnson/VKOR

From Proteopedia

Jump to: navigation, search

Vitamin K Epoxide Reductase

Overall Structure of Vitamin K Epoxide Reductase

Drag the structure with the mouse to rotate

References

  1. Liu S, Li S, Shen G, Sukumar N, Krezel AM, Li W. Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science. 2020 Nov 5. pii: science.abc5667. doi: 10.1126/science.abc5667. PMID:33154105 doi:http://dx.doi.org/10.1126/science.abc5667
  2. Jin DY, Tie JK, Stafford DW. The conversion of vitamin K epoxide to vitamin K quinone and vitamin K quinone to vitamin K hydroquinone uses the same active site cysteines. Biochemistry. 2007 Jun 19;46(24):7279-83. doi: 10.1021/bi700527j. Epub 2007 May, 25. PMID:17523679 doi:http://dx.doi.org/10.1021/bi700527j
  3. 3.0 3.1 Stafford DW. The vitamin K cycle. J Thromb Haemost. 2005 Aug;3(8):1873-8. doi: 10.1111/j.1538-7836.2005.01419.x. PMID:16102054 doi:http://dx.doi.org/10.1111/j.1538-7836.2005.01419.x
  4. 4.0 4.1 Blanchard RA, Furie BC, Jorgensen M, Kruger SF, Furie B. Acquired vitamin K-dependent carboxylation deficiency in liver disease. N Engl J Med. 1981 Jul 30;305(5):242-8. doi: 10.1056/NEJM198107303050502. PMID:6165889 doi:http://dx.doi.org/10.1056/NEJM198107303050502
  5. Swanson JC, Suttie JW. Vitamin K dependent in vitro production of prothrombin. Biochemistry. 1982 Nov 9;21(23):6011-8. doi: 10.1021/bi00266a044. PMID:6758841 doi:http://dx.doi.org/10.1021/bi00266a044
  6. 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 Liu S, Li S, Shen G, Sukumar N, Krezel AM, Li W. Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science. 2020 Nov 5. pii: science.abc5667. doi: 10.1126/science.abc5667. PMID:33154105 doi:http://dx.doi.org/10.1126/science.abc5667
  7. Shen G, Cui W, Cao Q, Gao M, Liu H, Su G, Gross ML, Li W. The catalytic mechanism of vitamin K epoxide reduction in a cellular environment. J Biol Chem. 2021 Jan-Jun;296:100145. doi: 10.1074/jbc.RA120.015401. Epub 2020, Dec 10. PMID:33273012 doi:http://dx.doi.org/10.1074/jbc.RA120.015401
  8. 8.0 8.1 Patel S, Singh R, Preuss CV, Patel N. Warfarin PMID:29261922
  9. Wu S, Chen X, Jin DY, Stafford DW, Pedersen LG, Tie JK. Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition. Blood. 2018 Aug 9;132(6):647-657. doi: 10.1182/blood-2018-01-830901. Epub 2018, May 9. PMID:29743176 doi:http://dx.doi.org/10.1182/blood-2018-01-830901
  10. 10.0 10.1 Chong YK, Mak TW. Superwarfarin (Long-Acting Anticoagulant Rodenticides) Poisoning: from Pathophysiology to Laboratory-Guided Clinical Management. Clin Biochem Rev. 2019 Nov;40(4):175-185. doi: 10.33176/AACB-19-00029. PMID:31857739 doi:http://dx.doi.org/10.33176/AACB-19-00029

Student Contributors

Kiana Jackson

Izabella Jordan

George Papadeas

Bianca Pontrelli

Anna Pressel

Emma Varness

Proteopedia Page Contributors and Editors (what is this?)

R. Jeremy Johnson

Personal tools