User:Wayne Decatur/SandboxYeastRibosome

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Yeast Ribosome based on Cryo-EM and RNA and Protein Homology Modeling

 
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The Eukaryotic (Budding Yeast) Ribosome
(optimized versions of 3jyx and 3jyw and 3jyv ), resolution 8.9Å ().

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Atomic model of a eukaryotic ribosome obtained by combined cryo-EM and RNA and protein homology modeling. Specifically, cryo-EM reconstruction of the 80S ribosome from the thermophilic fungus Thermomyces lanuginosus was used as a guide guide for building homology models of the S. cerevisiae ribosomal proteins and rRNA sequences that fit the cryo-EM map. .

About this Structure

This structure is a composite of 3 pdb files optimized for use online:
3jyx is a 3 chains structure of sequences from Thermomyces lanuginosus. Full crystallographic information is available from OCA.
3jyw is a 30 chains structure of sequences from Thermomyces lanuginosus. Full crystallographic information is available from OCA.
3jyv is a 19 chains structure of sequences from Thermomyces lanuginosus. Full crystallographic information is available from OCA.



Reference

  • Taylor DJ, Devkota B, Huang AD, Topf M, Narayanan E, Sali A, Harvey SC, Frank J. Comprehensive molecular structure of the eukaryotic ribosome. Structure. 2009 Dec 9;17(12):1591-604. PMID:20004163 doi:10.1016/j.str.2009.09.015

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Wayne Decatur

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