Vpu protein

From Proteopedia

HIV-1 Vpu protein (dark olive) complex with adapter-related protein complex 1 subunits γ-1 (gold), σ-1a (khaki), μ-1 (olive green), β-1 (green) (PDB code 4p6z) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Vpu protein (Vpu) or viral protein U is a viroporin encoded by HIV-1[1]. Vpu is a multifunctional enhancer of viral particle release[2]. (PDB code 4p6z). For details see HIV and accessory proteins.

3D Structures of Vpu protein

Updated on 25-January-2021

2n28 – Vpu - HIV-1 - NMR
1pi7, 1pi8, 1pje, 2gof, 2goh, 2jpx – Vpu trans-membrane domain - NMR
1vpu, 2n28, 2n29, 2k7y – Vpu cytoplasmic domain - NMR
4p6z – Vpu cytoplasmic domain + BST2 + AP-1 core

References

1. ↑ Gonzalez ME. Vpu Protein: The Viroporin Encoded by HIV-1. Viruses. 2015 Aug 4;7(8):4352-68. doi: 10.3390/v7082824. PMID:26247957 doi:http://dx.doi.org/10.3390/v7082824
2. ↑ Bour S, Strebel K. The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release. Microbes Infect. 2003 Sep;5(11):1029-39. PMID:12941395