2vrf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:29, 13 December 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2vrf.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN==
-
The line below this paragraph, containing "STRUCTURE_2vrf", creates the "Structure Box" on the page.
+
<StructureSection load='2vrf' size='340' side='right'caption='[[2vrf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2vrf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VRF FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
{{STRUCTURE_2vrf| PDB=2vrf | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vrf OCA], [https://pdbe.org/2vrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vrf RCSB], [https://www.ebi.ac.uk/pdbsum/2vrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vrf ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SNTB2_HUMAN SNTB2_HUMAN] Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/2vrf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vrf ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN===
+
==See Also==
-
 
+
*[[Syntrophin|Syntrophin]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2VRF is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VRF OCA].
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Bountra, C.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Cooper, C.]]
+
[[Category: Bountra C]]
-
[[Category: Doyle, D.]]
+
[[Category: Cooper C]]
-
[[Category: Edwards, A.]]
+
[[Category: Doyle D]]
-
[[Category: Elkins, J M.]]
+
[[Category: Edwards A]]
-
[[Category: Murray, J.]]
+
[[Category: Elkins JM]]
-
[[Category: Oppermann, U.]]
+
[[Category: Murray J]]
-
[[Category: Pike, A C.W.]]
+
[[Category: Oppermann U]]
-
[[Category: Pilka, E S.]]
+
[[Category: Pike ACW]]
-
[[Category: Roos, A K.]]
+
[[Category: Pilka ES]]
-
[[Category: Sun, Z.]]
+
[[Category: Roos AK]]
-
[[Category: Vondelft, F.]]
+
[[Category: Sun Z]]
-
[[Category: Actin cytoskeleton]]
+
[[Category: Von Delft F]]
-
[[Category: Actin-binding]]
+
-
[[Category: Adapter protein]]
+
-
[[Category: Alternative splicing]]
+
-
[[Category: Calcium]]
+
-
[[Category: Calmodulin-binding]]
+
-
[[Category: Cytoplasm]]
+
-
[[Category: Cytoplasmic vesicle]]
+
-
[[Category: Cytoskeleton]]
+
-
[[Category: Membrane]]
+
-
[[Category: Microtubule]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Polymorphism]]
+
-
[[Category: Protein-binding]]
+
-
[[Category: Snt3]]
+
-
[[Category: Sntb2]]
+
-
[[Category: Sntl]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:42:05 2009''
+

Current revision

CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN

PDB ID 2vrf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/2vrf"
Personal tools