5gpy
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the human TFIIE complex== | |
| + | <StructureSection load='5gpy' size='340' side='right'caption='[[5gpy]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5gpy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GPY FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gpy OCA], [https://pdbe.org/5gpy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gpy RCSB], [https://www.ebi.ac.uk/pdbsum/5gpy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gpy ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/T2EA_HUMAN T2EA_HUMAN] Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. | ||
| - | + | ==See Also== | |
| - | + | *[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Miwa | + | [[Category: Kojima R]] |
| - | [[Category: | + | [[Category: Miwa K]] |
| - | [[Category: | + | [[Category: Mizuguchi M]] |
| - | [[Category: | + | [[Category: Obita T]] |
| + | [[Category: Ohkuma Y]] | ||
| + | [[Category: Tamura Y]] | ||
Current revision
Crystal structure of the human TFIIE complex
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Categories: Homo sapiens | Large Structures | Kojima R | Miwa K | Mizuguchi M | Obita T | Ohkuma Y | Tamura Y
