3k5c
From Proteopedia
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===Human BACE-1 complex with NB-216=== | ===Human BACE-1 complex with NB-216=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3k5c]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K5C OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019963375</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Rondeau, J M.]] | [[Category: Rondeau, J M.]] | ||
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[[Category: Alzheimer's disease]] | [[Category: Alzheimer's disease]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
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[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Golgi apparatus]] | [[Category: Golgi apparatus]] | ||
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[[Category: Membrane]] | [[Category: Membrane]] | ||
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[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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Revision as of 09:42, 27 July 2012
Contents |
Human BACE-1 complex with NB-216
Template:ABSTRACT PUBMED 19963375
About this Structure
3k5c is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lerchner A, Machauer R, Betschart C, Veenstra S, Rueeger H, McCarthy C, Tintelnot-Blomley M, Jaton AL, Rabe S, Desrayaud S, Enz A, Staufenbiel M, Paganetti P, Rondeau JM, Neumann U. Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application. Bioorg Med Chem Lett. 2010 Jan 15;20(2):603-7. Epub 2009 Nov 22. PMID:19963375 doi:10.1016/j.bmcl.2009.11.092
