T-cell receptor 3D structures

3D structures of T-cell receptor

Updated on 22-November-2020 - For a general description of the protein see T-cell receptor

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• TCR α chain
  • 4udt – hTCR α chain variable domain + TRBV7-9 - human
    
  • 4udu – hTCR α chain variable domain + TRBV7-9 + enterotoxin type E
    
  • 1ac6, 1b88, 1h5b, 1i9e – mTCR α chain variable domain - mouse
    
  • 6mf8 – mTCR α chain transmembrane domain - NMR
    
• TCR β chain
  • 2axh – hTCR β chain (mutant)
    
  • 2axj – hTCR β chain
    
  • 2apb, 2apf, 2apt, 2apv, 2apw, 2apx – TCR β chain (mutant) - rat
    
  • 1bec – mTCR β chain
    
• TCR β chain + antigen
  • 1ktk, 3byt, 3byy, 3bzd – hTCR β chain (mutant) + exotoxin type C
    
  • 2ij0 – hTCR β chain + toxic shock syndrome toxin-1
    
  • 1jck, 1sbb, 1l0x, 1l0y, 2aq1, 2aq2, 2aq3, 3mc0 – mTCR β chain (mutant) + antigen
    
• TCR δ chain
  • 1tvd – hTCR δ chain variable domain
    
• TCR α+β chains
  • 1kgc, 2nw2, 2vlm, 3dx9, 3mff, 3qeu, 3skn, 4dzb, 4e42, 4jfh, 4g8f, 4g8e, 4ww1, 4x6b, 4zdh, 6eh4, 6eh5, 6eh6, 6eh7, 6eh8, 6eh9, 6fr6, 6fr7, 6fr8, 6fr9, 6fra, 6frb, 6frc, 6fum, 6fun, 6fuo, 6fup, 6fuq, 6fur, 6at6, 6fr3, 6fr4, 6fr5, 6ovo, 6cuh, 6cph, 5nmd, 6u07, 6vtc, 6vth, 6fr3 – hTCR α+β chains
    
  • 4ei6 – h/mTCR α+β chains
    
  • 2ial, 4gg8, 4onh – hTCR α+β chains (mutant)
    
  • 3of6 – hTCR pre-α+β (mutant) chains
    
  • 1tcr, 2z35, 2p1y – mTCR α+β chains
    
  • 1tcr, 2q86, 5iw1– mTCR α+β chains (mutant)
    
  • 1bwm – mTCR α+β chains variable domains (mutant) - NMR
    
• TCR α+β+γ chains
  • 4mnh – hTCR α+β+γ chains
    
• TCR γ+δ chains
  • 1hxm, 3omz – hTCR γ+δ chains
    
  • 4ndm – hTCR γ+δ chains (mutant)
    
• TCR complex with antigen
  • 2xna, 5fk9, 5fka – hTCR α+β chains + enterotoxin
    
  • [[6fra], 6fr6, 6fr7, 6fr8, 6fr9, 6frb, 6frc, 6fum, 6fun, 6fup, 6fuo 6fuq, 6fur, 4eh4, 6eh9, 6eh8, 6eh7, 4eh5, 6eh6 – hTCR α+β chains + polypeptide
    
  • 5tl5, 5tlj, 5tlk – h/mTCR α+β chains + CD27 antigen
    
  • 1nfd, 1kb5 – mTCR α+β chains + FAB fragment
    
• TCR complex with MHC and antigen
  • 1ao7, 1bd2, 1qrn, 1qse, 1qsf, 1mi5, 1oga, 1lp9, 2bnq, 2bnr, 2bnu, 2ak4, 2esv, 2f53, 2f54, 2gj6, 2nx5, 2p5e, 2p5w, 2pye, 2pyf, 3dxa, 3hg1, 3gsn, 3kpr, 3kps, 3kxf, 3o4l, 3qdg, 3qdj, 3qdm, 3qeq, 3sjv, 2ypl, 4jff, 4jfe, 4jfd, 4jry, 4jrx, 2jcc, 3d39, 3d3v, 4mji, 4prh, 4pri, 4prp, 5brz, 5bs0, 5c07, 5c08, 5c09, 5c0a, 5c0b, 5c0c, 5e6i, 5eu6, 5hhm, 5hho, 5hyj, 5ivx, 5ks9, 5ksa, 5ksb, 5m01, 5w1v, 5w1w, 5wkf, 5wkh, 6at6, 6avf, 6avg, 6bj2, 6bj3, 6bj8, 4nqc, 4nqd, 4nqe, 6rpb, 6rpa, 6rp9, 6q3s, 6dkp, 5yxu, 5yxn, 5nqk, 5nmg, 5nmf, 5nme, 5nht, 6l9l, 6dkp, 6q3s, 6tro, 6rpa, 6r2l – hTCR α+β chains + MHC + β-2 microglobulin + polypeptide
    
  • 1fyt, 1ymm, 1zgl, 4e41, 4z7u, 4z7v, 4z7w, 6u3o, 6u3n, 6py2, 6px6, 6cqr, 6cqq, 6cqn, 6cql – hTCR α+β chains + MHC + polypeptide
    
  • 4ozf, 4ozg, 4ozh, 4ozi, [2iam]], 2ian, 1j8h, 4gg6 – hTCR α+β chains (mutant) + MHC + polypeptide
    
  • 3o6f, 5u16, 5u17 – hTCR α+β chains + MHC
    
  • 3pl6 – hTCR α chain + MHC + polypeptide
    
  • 2xn9, 4c56 – hTCR α+β chains + MHC + polypeptide + enterotoxin
    
  • 5xot – hTCR δ+β chains + MHC + β-2 microglobulin + polypeptide
    
  • 1ypz, 6mwr – hTCR γ+δ chains + MHC + β-2 microglobulin
    
  • 4l4t, 4l4v, 4l8s, 4l9l, 4lcc, 4lcw, 5u1r, 5u2v, 5u6q, 5u72 – hTCR MAIT α+β chains + MHC + β-2 microglobulin
    
  • 2ckb, 1fo0, 1g6r, 1kj2, 1mwa, 1nam, 2ol3, 2j8u, 5til, 5tje, 6g9q – mTCR α+β chains + MHC + β-2 microglobulin + polypeptide
    
  • 2pxy – mTCR α+β chains (mutant) + MHC + β-2 microglobulin + polypeptide
    
  • 4p2o, 4p2q, 4p2r, 4p46 – mTCR α+β chains + MHC + polypeptide
    
  • 1u3h – mTCR α+β chains (mutant) + MHC + polypeptide
    
  • 2icw – mTCR α+β chains + MHC + mycoplasma arthritidis mitogen + polypeptide
    
  • 1d9k, 2e7l, 2oi9, 2z31, 3e2h, 3e3q, 3qib, 3mbe, 6bga – mTCR α+β chains + MHC + polypeptide
    
• TCR complex with CD
  • 4x6c, 4x6d – hTCR α+β chains + β-2 microglobulin + CD1A
    
  • 5wki, 6cug – hTCR α+β chains + β-2 microglobulin + CD1B
    
  • 6c09 – hTCR α+β chains + β-2 microglobulin + CD1C
    
  • 3huj, 3vwj, 3vwk, 4en3, 4ww2, 4wwk – hTCR NKT α+β chains + β-2 microglobulin + CD1D
    
  • 3tzv – hTCR NKT α+β chains (mutant) + β-2 microglobulin + CD1D
    
  • 3o8x, 3o9w, 4ei5, 4y16, 4y2d, 4y4h, 4y4k, 4y4f, 4zak, 6miv, 6mjq, 6mja, 6mji, 6mjj, 6mj4, 6mj6, 6miy – h/mTCR NKT α+β chains + β-2 microglobulin + CD1D
    
  • 3scm, 3sda, 3sdc, 3sdd, 3sdx – h/mTCR NKT α+β chains + β-2 microglobulin + CD1D + ceramide derivative
    
  • 3t0e – hTCR α+β chains + MHC + CD4
    
  • 6cxa, 6cx9, 6cx7, 6cx5, 6cwe, 6cwb, 6cw9, 6cw6, 5wlg, 5m02 – mTCR α+β chains + β-2 microglobulin + CD1D1
    
  • 6jxr – hTCR α+β+γ chains + CD3 – Cryo EM
    

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Michal Harel, Jaime Prilusky