2d4a

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Structure of the malate dehydrogenase from Aeropyrum pernix

Structural highlights

2d4a is a 4 chain structure with sequence from Aeropyrum pernix. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.87Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MDH_AERPE Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. Can utilize both NAD and NADP. Has a preference for NADP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Kawakami R, Sakuraba H, Goda S, Tsuge H, Ohshima T. Refolding, characterization and crystal structure of (S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. Biochim Biophys Acta. 2009 Oct;1794(10):1496-504. Epub 2009 Jun 23. PMID:19555779 doi:10.1016/j.bbapap.2009.06.014

Contents


PDB ID 2d4a

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