3muk

From Proteopedia

Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23

Structural highlights

3muk is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.75Å
Ligands:	EDO, PRK
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BRD4_MOUSE Plays a role in a process governing chromosomal dynamics during mitosis.^[1]

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Dey A, Ellenberg J, Farina A, Coleman AE, Maruyama T, Sciortino S, Lippincott-Schwartz J, Ozato K. A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition. Mol Cell Biol. 2000 Sep;20(17):6537-49. PMID:10938129

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 See Also
5 References

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PDB ID 3muk

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Categories: Homo sapiens | Large Structures | Mus musculus | Geyer M | Vollmuth F

3muk

From Proteopedia

Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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