Structural highlights
Function
PTHX1_XANOP Avirulence protein. Acts as a transcription factor in rice, inducing expression of a number of host genes including SWEET11 (Os8N3, XA13, AC Q6YZF3) in susceptible plants with the Xa13 allele. Plants with the xa13 allele, which has an altered promoter, are resistant to bacterial blight caused by this bacterial strain and do not induce SWEET11. The xa13 allele elicits an atypical hypersensitive response (HR). PthXo1 binds SWEET11 promoter DNA in a sequence-specific manner.[1] [2] [3] [4]
See Also
References
- ↑ Yang B, White FF. Diverse members of the AvrBs3/PthA family of type III effectors are major virulence determinants in bacterial blight disease of rice. Mol Plant Microbe Interact. 2004 Nov;17(11):1192-200. PMID:15553245 doi:10.1094/MPMI.2004.17.11.1192
- ↑ Yang B, Sugio A, White FF. Os8N3 is a host disease-susceptibility gene for bacterial blight of rice. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10503-10508. PMID:16798873 doi:10.1073/pnas.0604088103
- ↑ Römer P, Recht S, Strauß T, Elsaesser J, Schornack S, Boch J, Wang S, Lahaye T. Promoter elements of rice susceptibility genes are bound and activated by specific TAL effectors from the bacterial blight pathogen, Xanthomonas oryzae pv. oryzae. New Phytol. 2010 Sep;187(4):1048-1057. PMID:20345643 doi:10.1111/j.1469-8137.2010.03217.x
- ↑ Mak AN, Bradley P, Cernadas RA, Bogdanove AJ, Stoddard BL. The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target. Science. 2012 Jan 5. PMID:22223736 doi:10.1126/science.1216211
