7d46

From Proteopedia

eIF2B apo

Structural highlights

7d46 is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 4Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

EI2BA_HUMAN Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.

Function

EI2BA_HUMAN Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

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PDB ID 7d46

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Categories: Homo sapiens | Large Structures | Ito T | Kashiwagi K

7d46

From Proteopedia

eIF2B apo

Structural highlights

Disease

Function

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