Aromatase

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PDB ID 3EQM

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3D structures of aromatase

See human P450 19 family in Cytochrome P450


References

  1. Kagawa N. Efficient expression of human aromatase (CYP19) in E. coli. Methods Mol Biol. 2011;705:109-22. PMID:21125383 doi:10.1007/978-1-61737-967-3_7
  2. Conley A, Hinshelwood M. Mammalian aromatases. Reproduction. 2001 May;121(5):685-95. PMID:11427156
  3. 3.0 3.1 3.2 3.3 3.4 Ghosh, D., Griswold, J., Erman, M., Pangborn, W. " X-ray Structure of Human Aromatase Reveals An Androgen-Specific Active Site" Journal of Steroid Biochemistry and Molecular Biology. [Online] 2010,Vol. 118, Issue 4-5, p197-202. [1]
  4. 4.0 4.1 "Aromatase Products" [2]
  5. Favia AD, Cavalli A, Masetti M, Carotti A, Recanatini M. Three-dimensional model of the human aromatase enzyme and density functional parameterization of the iron-containing protoporphyrin IX for a molecular dynamics study of heme-cysteinato cytochromes. Proteins. 2006 Mar 1;62(4):1074-87. PMID:16395678 doi:10.1002/prot.20829
  6. "Aromatase Inhibitors" [3]
  7. Jones ME, Boon WC, McInnes K, Maffei L, Carani C, Simpson ER. Recognizing rare disorders: aromatase deficiency. Nat Clin Pract Endocrinol Metab. 2007 May;3(5):414-21. PMID:17452968 doi:10.1038/ncpendmet0477
  8. Stratakis CA, Vottero A, Brodie A, Kirschner LS, DeAtkine D, Lu Q, Yue W, Mitsiades CS, Flor AW, Chrousos GP. The aromatase excess syndrome is associated with feminization of both sexes and autosomal dominant transmission of aberrant P450 aromatase gene transcription. J Clin Endocrinol Metab. 1998 Apr;83(4):1348-57. PMID:9543166
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