Function
Cytochrome P450 (P450) or cytochrome P450 monooxygenase catalyzes the oxidation of organic substances like lipids. The P450 contains a heme cofactor. The protein is numbered by its gene.[1] P450 CYP121 is called mycocyclosin synthase.
- P450cam, also known as camphor 5-monooxygenase, catalyzes the hydroxylation of camphor.
- P450nor is a Nitric Oxide Reductase P450.
- P450epoK converts epothilone D to epothilone B.
- P450cin monooxygenates 1,8-cineole which is similar to camphor.
- Bifunctional P450/NADPH P450 reductase (P450 BM3) is a fatty acid monooxygenase.
- P450 3A4 see CYP3A4.
- P450 19 family see Aromatase.
- P450 17A1 see Human steroidogenic cytochrome P450 17A1 with inhibitor abiraterone
See also Hemeproteins.
Additional details on cytochrome P450 interactions with drugs see
Structural highlights
The . The .[2]
3D Structures of Cytochrome P450
Cytochrome P450 3D structures