Beta2 adrenergic receptor-Gs protein complex updated

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Adrenergic receptor (blue) complex with G protein α subunit (grey), β subunit (green), γ-2 subunit (gold), antibody fragment (Orchid) and benzoxazin derivative 3sn6, resolution 3.20Å

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References

  1. https://en.wikipedia.org/wiki/G_protein
  2. https://en.wikipedia.org/wiki/GTPase
  3. https://en.wikipedia.org/wiki/Small_GTPase
  4. https://en.wikipedia.org/wiki/Heterotrimeric_G_protein
  5. Hurowitz EH, Melnyk JM, Chen YJ, Kouros-Mehr H, Simon MI, Shizuya H. Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes. DNA Res. 2000 Apr 28;7(2):111-20. doi: 10.1093/dnares/7.2.111. PMID:10819326 doi:http://dx.doi.org/10.1093/dnares/7.2.111
  6. Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. Crystal structure of the beta2 adrenergic receptor-Gs protein complex. Nature. 2011 Jul 19;477(7366):549-55. doi: 10.1038/nature10361. PMID:21772288 doi:10.1038/nature10361

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Alexander Berchansky

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