Cobra venom factor

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Cobra Venom Factor α chain (red), β chain (blue), γ chain (yellow) complex with Ca+2 ion (red) (PDB entry 3frp)

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3D Structures of Cobra venom factor

Updated on 21-December-2022

3pvm, 8ayh – CVF + hComplement C5
3frp – CVF α,β,γ chains
3hrz – CVF α,β,γ chains + hComplement C5 (mutant)
3hs0 – CVF α,β,γ chains + hComplement B (mutant)
3prx – CVF α,β,γ chains + hComplement C5 + superantigen-like protein 7

References

  1. Vogel CW, Fritzinger DC, Hew BE, Thorne M, Bammert H. Recombinant cobra venom factor. Mol Immunol. 2004 Jun;41(2-3):191-9. PMID:15159065 doi:http://dx.doi.org/10.1016/j.molimm.2004.03.011
  2. Krishnan V, Ponnuraj K, Xu Y, Macon K, Volanakis JE, Narayana SV. The crystal structure of cobra venom factor, a cofactor for C3- and C5-convertase CVFBb. Structure. 2009 Apr 15;17(4):611-9. PMID:19368894 doi:10.1016/j.str.2009.01.015

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