Colonization factor antigen

From Proteopedia

spinqualitylabelsall models E. coli colonization factor antigen subunits B and E complex with sulfate and Na+ ion (purple) (PDB entry 3f83) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Colonization factor antigen (CFA) causes the bacterial infection of the small intestinal mucosa.[1] For details of the cholera bacterium CFA see Vibrio cholerae colonization factor TcpF.

3D Structures of colonization factor antigen

Updated on 09-June-2021

2hb0 – EcCFA I subunit E – Escherichia coli
3f84, 3f85, 4y2l, 4y2n – EcCFA I subunit B
6nrv – EcCFA I subunit B – Cryo EM
3vac – EcCFA I subunit E (mutant)
4y2o – EcCFA I subunit A (mutant)+B
3f83 – EcCFA I subunit B+E
3oc5 – CFA TcpF – Vibrio cholerae

References

1. ↑ Levine MM, Ristaino P, Marley G, Smyth C, Knutton S, Boedeker E, Black R, Young C, Clements ML, Cheney C, et al.. Coli surface antigens 1 and 3 of colonization factor antigen II-positive enterotoxigenic Escherichia coli: morphology, purification, and immune responses in humans. Infect Immun. 1984 May;44(2):409-20. PMID:6370866