FIS protein

From Proteopedia

FIS protein (Factor for Inversion Stimulation) or DNA-binding protein Fis is a regulatory protein in E. coli that activates ribosomal RNA transcription by binding to RNA promoter and enhances transcription by 5 to 10-fold. FIS binds to a sequence which stimulates hin-mediated DNA inversion and causes DNA bending. FIS affects the bacterial chromosome structure and the initiation of DNA replication. FIS exhibits autoregulation. It is abundant during E. coli exponential growth in rich medium and scarce during the stationary phase^[1].

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FIS protein complex with DNA 3jra

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3D Structures of FIS protein

Updated on 27-July-2021

1fia, 3fis, 4fis, 1ety – EcFIS - Escherichia coli
1f36, 1etk, 1eto, 1etq, 1etv, 1etw, 1etx – EcFIS (mutant)
1fip – EcFIS (mutant) + peptide
3iv5, 3jr9, 3jra, 3jrb, 3jrc, 3jrd, 3jre, 3jrf, 3jrg, 3jrh, 3jri, 4ihv, 4ihw, 4ihx, 4ihy, 5ds9, 5dtd, 5e3l, 5e3m, 5e3n, 5e3o, 6p0s – EcFIS + DNA
6p0t, 6p0u – EcFIS + DNA + exicionase

References

↑ Travers A, Schneider R, Muskhelishvili G. DNA supercoiling and transcription in Escherichia coli: The FIS connection. Biochimie. 2001 Feb;83(2):213-7. PMID:11278071

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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FIS protein

From Proteopedia

3D Structures of FIS protein

References

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