Function
Fatty acid synthase (FAS) catalizes the synthesis of palmitate from acetyl CoA and malonyl CoA into long chain fatty acid[1] . FAS is a multi-domain enzyme. It contains an acyl carrier protein domain (ACP). See also Lipid metabolism.
Relevance
FAS is as target of anti-cancer drugs. FAS from Mycobacterium tuberculosis inhibitors are possible anti-tuberculosis drugs[2] .
Structural insights
(Hydrophobic, Polar). The [3].
3D structures of fatty acid synthase
Fatty acid synthase 3D structures