Fluoxetine

Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Fluoxetine delays the reuptake of serotonin, resulting in serotonin persisting longer when it is released. See also [1] and Serotonin Transporter.

Leucine transporter LeuT in complex with R-fluoxetine (3gwv).

Fluoxetine binding site. Water molecules are shown as red spheres.