Follistatin

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Human follistatin-like 3 (cyan, green) complex with activin (pink, yellow) and sulfate (PDB code 3b4v)

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3D structures of follistatin

Updated on 29-July-2021

References

  1. Phillips DJ, de Kretser DM. Follistatin: a multifunctional regulatory protein. Front Neuroendocrinol. 1998 Oct;19(4):287-322. doi: 10.1006/frne.1998.0169. PMID:9799587 doi:http://dx.doi.org/10.1006/frne.1998.0169
  2. Tortoriello DV, Sidis Y, Holtzman DA, Holmes WE, Schneyer AL. Human follistatin-related protein: a structural homologue of follistatin with nuclear localization. Endocrinology. 2001 Aug;142(8):3426-34. PMID:11459787
  3. Lee SJ, Lee YS, Zimmers TA, Soleimani A, Matzuk MM, Tsuchida K, Cohn RD, Barton ER. Regulation of muscle mass by follistatin and activins. Mol Endocrinol. 2010 Oct;24(10):1998-2008. doi: 10.1210/me.2010-0127. Epub 2010, Sep 1. PMID:20810712 doi:http://dx.doi.org/10.1210/me.2010-0127
  4. Ogura Y, Ouchi N, Ohashi K, Shibata R, Kataoka Y, Kambara T, Kito T, Maruyama S, Yuasa D, Matsuo K, Enomoto T, Uemura Y, Miyabe M, Ishii M, Yamamoto T, Shimizu Y, Walsh K, Murohara T. Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models. Circulation. 2012 Oct 2;126(14):1728-38. doi: 10.1161/CIRCULATIONAHA.112.115089. , Epub 2012 Aug 28. PMID:22929303 doi:http://dx.doi.org/10.1161/CIRCULATIONAHA.112.115089
  5. Stamler R, Keutmann HT, Sidis Y, Kattamuri C, Schneyer A, Thompson TB. The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity. J Biol Chem. 2008 Nov 21;283(47):32831-8. Epub 2008 Sep 2. PMID:18768470 doi:10.1074/jbc.M801266200

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