Function
Gp41 is a subunit of the envelope protein of retrovirus[1]. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see HIV-1 viral envelope proteins.
Relevance
Fusion inhibitory drugs which bind to Gp41 prevent the attachment of the HIV-1 virus to the cell[2].
3D Structures of Gp41
Gp41 3D Structures