Oberholser, Karl

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Karl M. Oberholser (1942-2013) was a Professor of Chemistry in the Department of Chemistry and Biochemistry at Messiah College in Mechanicsburg PA USA from 1976-2010, and Professor Emeritus until his death from multiple myeloma in 2013. At Messiah, he created the Molecular Science Laboratory, a series of online molecular visualization tutorials designed for students. He authored many articles in Proteopedia (complete list), and in 2010 became a member of Proteopedia's Editorial Board.

Educational Articles and Tutorials

Some particularly noteworthy articles in Proteopedia that were initially authored by Karl Oberholser include:
Protein Structure

Protein Families

Specific Proteins

Nucleic Acid Structure



Oberholser mentored his student Emily Forschler who, while an undergraduate, authored the article Photosystem_II. Oberholser is quoted about the impact of Forschler's article in his class.

Oberholser's article Ramachandran Plot was used to illustrate the power of Proteopedia in Figure 3 in a 2008 publication about Proteopedia[2].

Oberholser also made significant contributions to many Proteopedia articles, initially written by other authors, and not listed above.


In addition to various scientific research publications from 1976-1998, Oberholser authored or coauthored the following publications:

  • Oberholser K. Proteopedia entry: Ramachandran plots. Biochem Mol Biol Educ. 2010 Nov;38(6):430. doi: 10.1002/bmb.20457. PMID:21567876 doi:10.1002/bmb.20457
  • Prilusky J, Hodis E, Canner D, Decatur W, Oberholser K, Martz E, Berchanski A, Harel M, Sussman JL. Proteopedia: A status report on the collaborative, 3D web-encyclopedia of proteins and other biomolecules. J Struct Biol. 2011 Apr 23. PMID:21536137 doi:10.1016/j.jsb.2011.04.011

Notes & References

  1. The original Collagen tutorial at Messiah College has been viewed over 20,000 times since 2007.
  2. Hodis E, Prilusky J, Martz E, Silman I, Moult J, Sussman JL. Proteopedia - a scientific 'wiki' bridging the rift between three-dimensional structure and function of biomacromolecules. Genome Biol. 2008;9(8):R121. Epub 2008 Aug 3. PMID:18673581 doi:http://dx.doi.org/10.1186/gb-2008-9-8-r121

Proteopedia Page Contributors and Editors (what is this?)

Eric Martz

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