Nuclear receptor coactivator

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Mouse nuclear receptor activator (green) complex with STAT6 transactivator domain LXXLL peptide (sky blue) and I-1 ions, 1oj5

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3D structures of nuclear receptor coactivator

Updated on 17-July-2024

2c52 – hNCOA1 residues 920-970 + CREB-binding protein – human
1kbh, 6es7, 6sqc – hNCOA3 1040-1086 + CREB-binding protein – NMR
1v95 – hNCOA5 anticodon binding domain 197-313 – human – NMR
8arp – hNCOA7 781-942
1oj5 – mNCOA1A Pas-B domain 257-367 + signal transducer and activator of transcription peptide – mouse
5y7w - mNCOA1A Pas-B domain + YL-2 peptide

References

  1. Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS, Tung L. Nuclear receptor coactivators and corepressors. Mol Endocrinol. 1996 Oct;10(10):1167-77. PMID:9121485 doi:http://dx.doi.org/10.1210/mend.10.10.9121485
  2. Peng Z, Li Y, Xia S, Dai Q, Yin L, Chen M, Yang W, Shao G, Lin Q. Expression of nuclear receptor co‑activator 7 protein is associated with poor prognosis of breast cancer. Oncol Lett. 2024 Apr 23;27(6):278. PMID:38699661 doi:10.3892/ol.2024.14411

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