Platelet-derived growth factors and receptors

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Platelet-Derived Growth Factor Receptor (brown and turquoise) complex with Platelet-Derived Growth Factor B (grey and green) (PDB code 3mjg)

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3D structures of platelet-derived growth factor receptor

Updated on 03-September-2023


  1. Heldin CH, Ostman A, Eriksson A, Siegbahn A, Claesson-Welsh L, Westermark B. Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes. Kidney Int. 1992 Mar;41(3):571-4. PMID:1315403
  2. Shim AH, Liu H, Focia PJ, Chen X, Lin PC, He X. Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11307-12. Epub 2010 Jun 2. PMID:20534510
  3. Heldin CH, Westermark B. Platelet-derived growth factor: three isoforms and two receptor types. Trends Genet. 1989 Apr;5(4):108-11. PMID:2543106
  4. Williams LT. Signal transduction by the platelet-derived growth factor receptor. Science. 1989 Mar 24;243(4898):1564-70. PMID:2538922
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