RNase A

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This page, as it appeared on October 8, 2011, was featured in this article in the journal Biochemistry and Molecular Biology Education.

Bovine Pancreatic Ribonuclease A (RNase A), 7rsa

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Additional Proteopedia Pages about RNase A

3D structures of ribonuclease



  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Raines RT. Ribonuclease A. Chem Rev. 1998 May 7;98(3):1045-1066. PMID:11848924
  2. Avey HP, Boles MO, Carlisle CH, Evans SA, Morris SJ, Palmer RA, Woolhouse BA, Shall S. Structure of ribonuclease. Nature. 1967 Feb 11;213(5076):557-62. PMID:6032249
  3. Wyckoff HW, Hardman KD, Allewell NM, Inagami T, Johnson LN, Richards FM. The structure of ribonuclease-S at 3.5 A resolution. J Biol Chem. 1967 Sep 10;242(17):3984-8. PMID:6037556
  4. Greenway MJ, Andersen PM, Russ C, Ennis S, Cashman S, Donaghy C, Patterson V, Swingler R, Kieran D, Prehn J, Morrison KE, Green A, Acharya KR, Brown RH Jr, Hardiman O. ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis. Nat Genet. 2006 Apr;38(4):411-3. Epub 2006 Feb 26. PMID:16501576 doi:10.1038/ng1742
  5. 5.0 5.1 5.2 'Lehninger A., Nelson D.N, & Cox M.M. (2008) Lehninger Principles of Biochemistry. W. H. Freeman, fifth edition.'
  6. 6.0 6.1 6.2 Wlodawer A, Svensson LA, Sjolin L, Gilliland GL. Structure of phosphate-free ribonuclease A refined at 1.26 A. Biochemistry. 1988 Apr 19;27(8):2705-17. PMID:3401445
  7. Birdsall DL, McPherson A. Crystal structure disposition of thymidylic acid tetramer in complex with ribonuclease A. J Biol Chem. 1992 Nov 5;267(31):22230-6. PMID:1429575
  8. delCardayre SB, Raines RT. Structural determinants of enzymatic processivity. Biochemistry. 1994 May 24;33(20):6031-7. PMID:8193116
  9. Thompson JE, Raines RT. Value of general Acid-base catalysis to ribonuclease a. J Am Chem Soc. 1994 Jun;116(12):5467-8. PMID:21391696 doi:10.1021/ja00091a060
  10. Fontecilla-Camps JC, de Llorens R, le Du MH, Cuchillo CM. Crystal structure of ribonuclease A.d(ApTpApApG) complex. Direct evidence for extended substrate recognition. J Biol Chem. 1994 Aug 26;269(34):21526-31. PMID:8063789
  11. Kobe B, Deisenhofer J. A structural basis of the interactions between leucine-rich repeats and protein ligands. Nature. 1995 Mar 9;374(6518):183-6. PMID:7877692 doi:http://dx.doi.org/10.1038/374183a0
  12. Turcotte RF, Raines RT. Interaction of onconase with the human ribonuclease inhibitor protein. Biochem Biophys Res Commun. 2008 Dec 12;377(2):512-4. Epub 2008 Oct 16. PMID:18930025 doi:10.1016/j.bbrc.2008.10.032

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