Retinoblastoma protein

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Human retinoblastoma protein pocket domain dimer (grey and green) complex with papilloma virus E7 peptide (magenta) , 1gux

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3D structures of retinoblastoma protein

Updated on 13-February-2022


  2. Xiao B, Spencer J, Clements A, Ali-Khan N, Mittnacht S, Broceno C, Burghammer M, Perrakis A, Marmorstein R, Gamblin SJ. Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2363-8. Epub 2003 Feb 21. PMID:12598654 doi:10.1073/pnas.0436813100
  3. 3.0 3.1 3.2 3.3 3.4
  4. Nevins JR. The Rb/E2F pathway and cancer. Hum Mol Genet. 2001 Apr;10(7):699-703. PMID:11257102
  5. 5.0 5.1 Liu X, Marmorstein R. Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. Genes Dev. 2007 Nov 1;21(21):2711-6. PMID:17974914 doi:21/21/2711

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