Salt bridges

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Salt bridge between retinoic acid(-) and arg131(+) in 1cbr.

Visualization

Putative protein-protein salt bridges involving charged amino acid sidechains and/or charged chain termini can be displayed by FirstGlance in Jmol. Salt bridges to ligands can be visualized using the Contacts & Non-covalent interactions tool, after selecting the ligand as the target for the display. Such a case is illustrated above in JSmol.

References

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  2. Jeffrey, George A., An introduction to hydrogen bonding, Oxford University Press, 1997. Page 192.
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  8. Chan CH, Yu TH, Wong KB. Stabilizing salt-bridge enhances protein thermostability by reducing the heat capacity change of unfolding. PLoS One. 2011;6(6):e21624. Epub 2011 Jun 24. PMID:21720566 doi:10.1371/journal.pone.0021624
  9. Bandyopadhyay AK, Islam RNU, Mitra D, Banerjee S, Goswami A. Stability of buried and networked salt-bridges (BNSB)in thermophilic proteins. Bioinformation. 2019 Feb 3;15(1):61-67. doi: 10.6026/97320630015061. eCollection , 2019. PMID:31360001 doi:http://dx.doi.org/10.6026/97320630015061
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