Talin
From Proteopedia
Talin is involved in cell-cell contacts. It links integrins to actin[1]. It contains a C-terminal rod domain with integrin binding sites (IBS) and actin binding sites (ABS) and N-terminal FERM domain with subdomains F1-F3. The F3 subdomain interacts with integrin. Talin contains 3 Vinculin binding sites VBS1-VBS3. |
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3D Structures of Talin
References
- ↑ Critchley DR. Biochemical and structural properties of the integrin-associated cytoskeletal protein talin. Annu Rev Biophys. 2009;38:235-54. doi: 10.1146/annurev.biophys.050708.133744. PMID:19416068 doi:http://dx.doi.org/10.1146/annurev.biophys.050708.133744
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