Tetherin

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Glycosylated human tetherin ectodomain dimer 2xg7

3D structures of tetherin

Updated on 23-November-2020

2x7a, 3nwh, 2xg7, 3mqb, 3mqc – hBST-2 ectodomain – human
3mq7, 3mq9 - hBST-2 ectodomain (mutant)
2lk9 – hBST-2 transmembrane (mutant) – NMR
4p6z – hBST-2 in adaptor protein complex
6cm9, 6owt, 6cri, 6d83, 6d84, 6dff – hBST-2/Nef in adaptor protein complex – Cryo EM
3ni0 - BST-2 ectodomain – mouse


References

Sakuma, Noda, Urata, Kawaoka, & Yasuda (2009). Inhibition of Lassa and Marburg Virus Production by Tetherin. Journal of Virology. 83:2382-2385.

Neil, Zang, & Beiniasz (2008). Tetherin inhibits retroviral release and is antagonized by HIV-1 Vpu. Nature. 451: 425-430.

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Michal Harel, Kim Smith, Alexander Berchansky, David Canner

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