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E. coli TolB (PDB code 1c5k)

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3D structures of TolB

Updated on 25-April-2022

1crz, 1c5k – EcTolB – Escherichia coli
2ivz – EcTolB + colicin-E9 T-domain
4jml - EcTolB (mutant) + colicin-E9 T-domain (mutant)
7nst - EcTolB (mutant) + colicin-E9 + outer membrane protein F – Cryo EM
7nsu - EcTolB (mutant) + colicin-E9 + outer membrane protein F + BtuB – Cryo EM
3iax - EcTolB + colicin-A translocation domain
2hqs, 2w8b - EcTolB + peptidoglycan-associated lipoprotein
4pwz – YpTolB – Yersinia pestis
4r40 - YpTolB + peptidoglycan-associated lipoprotein
6pnv – TolB – Salmonella enterica
7mx5 – TolB – Acinetobacteria baumannii


  1. 1.0 1.1 Bouveret E, Derouiche R, Rigal A, Lloubes R, Lazdunski C, Benedetti H. Peptidoglycan-associated lipoprotein-TolB interaction. A possible key to explaining the formation of contact sites between the inner and outer membranes of Escherichia coli. J Biol Chem. 1995 May 12;270(19):11071-7. PMID:7744736
  2. 2.0 2.1 2.2 2.3 Bonsor DA, Hecht O, Vankemmelbeke M, Sharma A, Krachler AM, Housden NG, Lilly KJ, James R, Moore GR, Kleanthous C. Allosteric beta-propeller signalling in TolB and its manipulation by translocating colicins. EMBO J. 2009 Sep 16;28(18):2846-57. Epub 2009 Aug 20. PMID:19696740 doi:10.1038/emboj.2009.224
  3. Rigal A, Bouveret E, Lloubes R, Lazdunski C, Benedetti H. The TolB protein interacts with the porins of Escherichia coli. J Bacteriol. 1997 Dec;179(23):7274-9. PMID:9393690
  4. Godlewska R, Wisniewska K, Pietras Z, Jagusztyn-Krynicka EK. Peptidoglycan-associated lipoprotein (Pal) of Gram-negative bacteria: function, structure, role in pathogenesis and potential application in immunoprophylaxis. FEMS Microbiol Lett. 2009 Sep;298(1):1-11. Epub 2009 May 21. PMID:19519769 doi:10.1111/j.1574-6968.2009.01659.x

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