User:Krishna Reddy Ragupathi

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One of the CBI Molecules being studied in the University of Massachusetts Amherst Chemistry-Biology Interface Program at UMass Amherst and on display at the Molecular Playground.

Carbonic Anhydrase

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Shown is the enzyme Carbonic Anhydrase II which falls under α-Family of Carbonic Anhydrases. As the name suggest Carbonic Anhydrases are a class of enzymes which catalyze the reversible conversion of carbondioxide to the bicarbonate and proton. Due to this unique property they play a key role in maintaining the acid-base balance of blood and several other tissues.


The active site of the enzyme is depicted here, which has three histidine residues coordinated to the zinc metal.

Proteopedia Page Contributors and Editors (what is this?)

Krishna Reddy Ragupathi, Eran Hodis

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