Serpin 3D structures

Updated on 19-November-2023 - For a general description of the protein see Serpin

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• Serpin
  • 5hgc – Ser – zebra finch
    
  • 1mtp, 1sng – Ser – Thermobifida fusca
• Serpin A1 see Alpha-1-antitrypsin
• Serpin A3 (α 1-antichymotrypsin)
  • 2ach, 1as4, 3caa, 6hgd, 6hge, 6hgh, 6hgm, 6hgn – hSer-A3 - human
    
  • 4caa, 1qmn, 3dlw – hSer-A3 (mutant)
    
  • 6hgf, 6hgg – hSer-A3 + cortisol
    
  • 6hgi, 6hgj, 6hgk, 6hgl – hSer-A3 + corticoid hormone
    
  • 5om2, 5om3, 5om5, 5om6, 5om7, 5om8, 6ftp – hSer-A3 (mutant) + antibiotic
    
  • 1yxa – mSer-A3N - mouse
    
• Ser A4 (kallistatin)
  • 6f4u, 6f02 – hSer-A4
    
  • 6f4v – hSer-A4 + heparin
    
• Serpin A5
  • 2ol2 – hSer-A5
    
  • 3dy0 – hSer-A5 + heparin
• Serpin A6 see Corticosteroid-binding globulin
• Serpin A7 or thyroxine-binding globulin
  • 2riv – hSer-A7
    
  • 2riw, 4x30 – hSer-A7 + thyroxine
    
  • 2xn3 – hSer-A7 + mefenamic acid
    
  • 2xn5 – hSer-A7 + furosemide
    
  • 2xn6, 2xn7 – hSer-A7 + thyroxine-fluoresein
    
  • 4yia - hSer-A7 + indomethacin
    
• Serpin A8 or angiotensin-II or angiotensinogen
  • 2jp8 – hSer-A8 – NMR
    
  • 2wxw, 5m3x, 5m3y – hSer-A8
    
  • 6i3i – hSer-A8 (mutant)
    
  • 2x0b – hSer-A8 + renin
    
  • 6i3f – hSer-A8 (mutant) + renin
    
  • 5e2q – hSer-A8 + DPP
    
  • 4fys – hSer-A8 + CD13
    
  • 2wxx, 2wxy, 2wy0 – mSer-A8
    
  • 2wxz, 2wy1 – rSer-A8 - rat
    
  • 8h55 – Ser-A8 - zebrafish
    
• Serpin A10 or protein Z-dependent protease inhibitor
  • 4afx, 4aju – hSer-A10 (mutant)
    
  • 3h5c, 3f1s – hSer-A10 + vitamin K-dependent protein Z
    
  • 4ajt – mSer-A10
    
• Serpin A12 (Vaspin)
  • 4if8 – hSer-A12
    
  • 4y3k, 4y40 – hSer-A12 (mutant)
    
  • 5ei0 – Ser-A12 – Escherichia coli
    
• Serpin A18
  • 4r9i – Ser-A18 – bee
    
• Serpin B1 (leukocyte elastase inhibitor)
  • 4ga7 – hSer-B1 (mutant)
    
  • 1hle – Ser-B1 – horse
    
• Serpin B3
  • 2zv6, 4zk3 – hSer-B3
• Serpin B4
  • 4zk0 – hSer-B4
    
• Serpin B5 (Maspin)
  • 1xqg, 1wz9, 1xu8 - hSer-B5
    
  • 1xqj – hSer-B5 (mutant)
    
• Serpin B9
  • 8h4x – hSer-B9
    
• Serpin C1 see Antithrombin
• Ser crmA (ice inhibitor)
  • 1c8o, 1f0c, 1m93 – cvSer-crmA (mutant) – cowpox virus
    
• Serpin E1 see Plasminogen activator inhibitor
• Serpin E2 or Gila-derived nexin
  • 4dy0 – hSer-E2 + heparin
    
  • 4dy7 – hSer-E2 + thrombin
    
• Serpin I1 (Neuroserpin)
  • 3fgq, 2f02, 3f5n – hSer-I1
    
  • 1jjo – mSer-I1
    
• Serpin iripin
  • 7qtz – tSer-Ir-1 – tick
    
  • 7ahp – tSer-Ir-3
    
  • 7zas, 7zbf – tSer-Ir-4
    
  • 7b2t – tSer-Ir-5
    
  • 7pnu – tSer-Ir-8
    
• Serpin K
  • 1sek – ThSer-K – Tobacco hornworm
• Serpin 1
  • 1k9o – ThSer-1 (mutant) + trypsin II
    
  • 3le2 – Ser-1 – Arabidopsis thaliana
    
  • 6bj5 – Ser-1 – Myxoma virus
    
• Serpin 2
  • 3nda – Ser-2 – Sheep tick
    
  • 3pzf – mmSer-2 – malaria mosquito
    
  • 4ro9, 4roa, 4rob, 4rsq – mmSer-2 (mutant)
    
  • 1m93 – cvSer-2
    
• Serpin 4 (Serine protease inhibitor 4)
  • 4p0f, 4p0o – Ser-4 – Drosophila melanogaster
    
• Serpin 8
  • 7pmu – Ser-8 – Ixodes ricinus
    
• Serpin 12
  • 6cj7 – Ser-12 – Manduca sexta
    
• Serpin 18
  • 4r9i – Ser-18 - silkworm
    
• Serpin 48
  • 3ozq – Ser-48 - mealworm
    

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Michal Harel, Jaime Prilusky