From Proteopedia

Jump to: navigation, search

Bovine aconitase showing FeS4 cluster complex with sulfate (PDB code 1amj)

Drag the structure with the mouse to rotate


  • M. Claire Kennedy and Helmut Beinert: IX.4. Aconitase. in Ivano Bertini, Harry B. Gray, Edward I. Stiefel, Joan Selverstone Valentine (eds.): Biological Inorganic Chemistry: Structure and Reactivity. University Science Books, Herndon 2006. ISBN 1891389432 pp.209--

Additional Resources

For additional information, see: Carbohydrate Metabolism; Krebs cycle step 2.


  1. Zheng L, Kennedy MC, Beinert H, Zalkin H. Mutational analysis of active site residues in pig heart aconitase. J Biol Chem. 1992 Apr 15;267(11):7895-903. PMID:1313811
  2. 2.0 2.1 Frishman D, Hentze MW. Conservation of aconitase residues revealed by multiple sequence analysis. Implications for structure/function relationships. Eur J Biochem. 1996 Jul 1;239(1):197-200. PMID:8706708
  3. Dupuy J, Volbeda A, Carpentier P, Darnault C, Moulis JM, Fontecilla-Camps JC. Crystal structure of human iron regulatory protein 1 as cytosolic aconitase. Structure. 2006 Jan;14(1):129-39. PMID:16407072 doi:10.1016/j.str.2005.09.009
  4. 4.0 4.1 4.2 Beinert, H., Kennedy, M. C., Stout, C.D. “Aconitase as Iron−Sulfur Protein, Enzyme, and Iron-Regulatory Protein.” Chem. Rev. 1996, 96, 2335−2373.
  5. Lauble H, Kennedy MC, Beinert H, Stout CD. Crystal structures of aconitase with trans-aconitate and nitrocitrate bound. J Mol Biol. 1994 Apr 8;237(4):437-51. PMID:8151704 doi:
  6. 6.0 6.1 6.2 6.3 Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry Life at the Molecular Level. New York: John Wiley & Sons, 2008. p. 578-579. Print.
  7. 7.0 7.1 Flint, DH., and Allen, RM. "Iron-sulfur protein with nonredox functions.” Chem. Rev. 1996, 96, 2315−2334.

External links

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Ralf Stephan, David Canner, Joel L. Sussman, Jaime Prilusky, Anthony Noles, Angel Herraez, Eran Hodis

Personal tools