Phosphoinositide phosphatase

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Human 5PTase complex with phosphoinositol 4-phospate, glycerol, sulfate, Cl- (green) and Mg+2 (light green) ions (PDB code 3mtc)

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3D Structures of phosphoinositide phosphatase

Updated on 04-August-2019


  1. Dyson JM, Fedele CG, Davies EM, Becanovic J, Mitchell CA. Phosphoinositide phosphatases: just as important as the kinases. Subcell Biochem. 2012;58:215-79. doi: 10.1007/978-94-007-3012-0_7. PMID:22403078 doi:
  2. Liu Y, Bankaitis VA. Phosphoinositide phosphatases in cell biology and disease. Prog Lipid Res. 2010 Jul;49(3):201-17. doi: 10.1016/j.plipres.2009.12.001. Epub, 2010 Jan 5. PMID:20043944 doi:
  3. Tresaugues L, Silvander C, Flodin S, Welin M, Nyman T, Graslund S, Hammarstrom M, Berglund H, Nordlund P. Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases. Structure. 2014 Apr 2. pii: S0969-2126(14)00073-2. doi:, 10.1016/j.str.2014.01.013. PMID:24704254 doi:

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