Prolactin

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Human prolactin (grey) complex with prolactin receptor extracellular domain (green), Na+ (purple) and Ca+2 (green) ions (PDB code 3mzg).

3D Structures of prolactin

Updated on 07-October-2020

1rw5 – hPRL – human - NMR
2q98 – hPRL (mutant)
3mzg, 3npz – hPRL + hPRL receptor extracellular domain
3d48, 3n06, 3n0p, 3ncb – hPRL (mutant) + hPRL receptor extracellular domain
3ncc, 3nce, 3ncf – hPRL (mutant) + hPRL receptor extracellular domain (mutant)
3ew3 – hPRL + rPRL receptor extracellular domain - rat

References

  1. Freeman ME, Kanyicska B, Lerant A, Nagy G. Prolactin: structure, function, and regulation of secretion. Physiol Rev. 2000 Oct;80(4):1523-631. PMID:11015620
  2. Chuang E, Molitch ME. Prolactin and autoimmune diseases in humans. Acta Biomed. 2007;78 Suppl 1:255-61. PMID:17465339

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Michal Harel

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