Pyruvate decarboxylase

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Pyruvate decarboxylate complex with phosphono ester, citrate and Mg+2 ion (green) (PDB code 1zpd)

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3D structures of pyruvate decarboxylase

Updated on 23-June-2022

Additional Resources

For additional information, see: Carbohydrate Metabolism


  1. Garrett, R.H., & Grisham, C.M. (2007). Biochemistry. Belmont, CA: Thompson.
  2. Dobritzsch D, Konig S, Schneider G, Lu G. High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases. J Biol Chem. 1998 Aug 7;273(32):20196-204. PMID:9685367
  3. Sergienko EA, Jordan F. Catalytic acid-base groups in yeast pyruvate decarboxylase. 3. A steady-state kinetic model consistent with the behavior of both wild-type and variant enzymes at all relevant pH values. Biochemistry. 2001 Jun 26;40(25):7382-403. PMID:11412092
  4. PMID:PMID: 8974393
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