Ion channels 3D structures: Difference between revisions

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
* Potassium channel See: [[Potassium_Channel#Additional_Structures_of_Potassium_Channels|Potassium Channels]]


*Calcium channel
*Calcium channel


**[[2d46]] – hVDCC 4a – NMR – human
**[[2d46]] – hVDCC beta 4a – NMR – human
**[[6nq0]], [[6nq1]], [[6nq2]] – hTpc2 – Cryo EM  <br />
**[[6nq0]], [[6nq1]], [[6nq2]] – hTpc2 – Cryo EM  <br />
**[[8if4]] – hCav alpha-2+delta-1 – Cryo EM  <br />
**[[8if4]] – hCav alpha-2+delta-1 – Cryo EM  <br />
**[[8if3]] – hCav alpha-2+delta-1 + drug – Cryo EM  <br />
**[[8if3]] – hCav alpha-2+delta-1 + drug – Cryo EM  <br />
**[[2be6]], [[2f3y]], [[2f3z]] – hCav1.2 1C subunit+calmodulin  
**[[2be6]], [[2f3y]], [[2f3z]] – hCav1.2 alpha 1C subunit+calmodulin  
**[[3oxq]] - hCav2.1 1C subunit IQ domain+hCalmodulin
**[[3oxq]] - hCav2.1 alpha 1C subunit IQ domain+hCalmodulin
**[[2vay]], [[3oxq]] – hCav1.1 1S subunit IQ domain+hCalmodulin
**[[2vay]], [[3oxq]] – hCav1.1 alpha 1S subunit IQ domain+hCalmodulin
**[[8eoi]] – hCav1.2 in EMC chaperone – Cryo EM  <br />
**[[8eoi]] – hCav1.2 in EMC chaperone – Cryo EM  <br />
**[[8fd7]] – hCav1.2 + drug – Cryo EM  <br />
**[[8fd7]] – hCav1.2 + drug – Cryo EM  <br />
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**[[6jpa]], [[6jpb]] – rCav1.1 + blocker – Cryo EM<br />
**[[6jpa]], [[6jpb]] – rCav1.1 + blocker – Cryo EM<br />
**[[8e56]], [[8e57]], [[8e58]] – rCav1.1 + drug – Cryo EM<br />
**[[8e56]], [[8e57]], [[8e58]] – rCav1.1 + drug – Cryo EM<br />
**[[3bxx]] – rCav2.1 1A subunit+calmodulin  
**[[3bxx]] – rCav2.1 alpha 1A subunit+calmodulin  
**[[3bxl]] - rCav2.3 1E subunit+calmodulin
**[[3bxl]] - rCav2.3 alpha 1E subunit+calmodulin
**[[1t0h]] – rVDCC 2A subunit  
**[[1t0h]] – rVDCC beta 2A subunit  
**[[1t0j]] – rVDCC 2A+ 1C  
**[[1t0j]] – rVDCC beta 2A+ 1C  
**[[1vyt]] - rVDCC 3+ 1C  
**[[1vyt]] - rVDCC beta 3+ 1C  
**[[1vyu]] – rVDCC 3
**[[1vyu]] – rVDCC beta 3
**[[1vyv]] - rVDCC 4
**[[1vyv]] - rVDCC beta 4
**[[6hw2]] - rVDCC 4 + chromobox protein<br />
**[[6hw2]] - rVDCC beta 4 + chromobox protein<br />
**[[1t3l]] - rVDCC 2+ 1S  
**[[1t3l]] - rVDCC beta 2+ 1S  
**[[1t3s]] - rVDCC 2
**[[1t3s]] - rVDCC beta 2
**[[3dve]], [[3dvj]], [[3dvk]], [[3dvm]], [[3g43]] - rCav2.2 1B subunit+hCalmodulin
**[[3dve]], [[3dvj]], [[3dvk]], [[3dvm]], [[3g43]] - rCav2.2 alpha 1B subunit+hCalmodulin
**[[4dex]] - rCav2.2 1B + 2 subunits<br />
**[[4dex]] - rCav2.2 alpha 1B + beta 2 subunits<br />
**[[4dey]] - rCav2.2 1C + 2 subunits<br />
**[[4dey]] - rCav2.2 alpha 1C + beta 2 subunits<br />
**[[6byo]] – rCav1.1 1S <br />
**[[6byo]] – rCav1.1 alpha 1S <br />
**[[5gjw]] – rCav1.1 2/d 1 + 1S +  1 – Cryo EM<br />
**[[5gjw]] – rCav1.1 alpha 2/d 1 + alpha 1S +  beta 1 – Cryo EM<br />
**[[3jbr]], [[5gjv]] – rCav1.1 2/d 1 + 1S +  1 + g 1 – Cryo EM<br />
**[[3jbr]], [[5gjv]] – rCav1.1 alpha 2/d 1 + alpha 1S +  beta 1 + gamma 1 – Cryo EM<br />
**[[5v2p]], [[5v2q]] - raCav1.2 1C + 2 - rat<br />
**[[5v2p]], [[5v2q]] - raCav1.2 alpha 1C + beta 2 - rat<br />
**[[7qhh]] - raVDCC g 8 + glutamate receptor 1 – Cryo EM<br />
**[[7qhh]] - raVDCC g 8 + glutamate receptor 1 – Cryo EM<br />
**[[5kk2]], [[5vov]], [[5vou]], [[5vot]] - raVDCC g 2 + glutamate receptor 2 – Cryo EM<br />
**[[5kk2]], [[5vov]], [[5vou]], [[5vot]] - raVDCC gamma 2 + glutamate receptor 2 – Cryo EM<br />
**[[6njl]], [[6njm]], [[6njn]] - raVDCC g 2 + glutamate receptor 1 + glutamate receptor 2 + a’/c’ auxiliary protein + antibody – Cryo EM<br />
**[[6njl]], [[6njm]], [[6njn]] - raVDCC gamma 2 + glutamate receptor 1 + glutamate receptor 2 + a’/c’ auxiliary protein + antibody – Cryo EM<br />
**[[6qkc]], [[6qkz]], [[7ocd]] - raVDCC g 8 + glutamate receptor 1 + glutamate receptor 2 – Cryo EM<br />
**[[6qkc]], [[6qkz]], [[7ocd]] - raVDCC gamma 8 + glutamate receptor 1 + glutamate receptor 2 – Cryo EM<br />
**[[7oca]], [[7oce]], [[7ocf]] - raVDCC g 8 + glutamate receptor 1 + glutamate receptor 2 + CNIH-2 – Cryo EM<br />
**[[7oca]], [[7oce]], [[7ocf]] - raVDCC gamma 8 + glutamate receptor 1 + glutamate receptor 2 + CNIH-2 – Cryo EM<br />
**[[8e0e]] – raCav L-type  2 + nanobody<br />
**[[8e0e]] – raCav L-type  beta 2 + nanobody<br />
**[[6c96]], [[6c9a]] – mTpc1 - mouse – Cryo EM <br />
**[[6c96]], [[6c9a]] – mTpc1 - mouse – Cryo EM <br />
**[[4zw2]] – mVDCC 1S peptide +  1 <br />
**[[4zw2]] – mVDCC alpha 1S peptide +  beta 1 <br />
**[[7lep]] - mVDCC g 8 + glutamate receptor 2 + AMPAR subunits + CNIH-2 – Cryo EM<br />
**[[7lep]] - mVDCC g 8 + glutamate receptor 2 + AMPAR subunits + CNIH-2 – Cryo EM<br />
**[[8dam]] – mCav L-type  1 + nanobody<br />
**[[8dam]] – mCav L-type  beta 1 + nanobody<br />
**[[5dqq]], [[5e1j]], [[5tua]], [[7fhk]], [[7fhl]] – AtTpc1 – Arabidopsis thaliana  <br />
**[[5dqq]], [[5e1j]], [[5tua]], [[7fhk]], [[7fhl]] – AtTpc1 – Arabidopsis thaliana  <br />
**[[6cx0]] – AtTpc1 (mutant) <br />
**[[6cx0]] – AtTpc1 (mutant) <br />
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**[[2yks]], [[3uq4]], [[3uq5]], [[3uq7]], [[4twh]], [[5hej]], [[5heo]], [[5heu]], [[5hew]] – EchELIC (mutant)
**[[2yks]], [[3uq4]], [[3uq5]], [[3uq7]], [[4twh]], [[5hej]], [[5heo]], [[5heu]], [[5hew]] – EchELIC (mutant)
**[[6v03]], [[6v0b]], [[8d63]], [[8d64]], [[8d65]], [[8f35]], [[8twz]], [[9ngf]], [[9ngg]], [[9ngq]], [[9ngr]], [[9ngs]] - EchELIC – Cryo EM<br />
**[[6v03]], [[6v0b]], [[8d63]], [[8d64]], [[8d65]], [[8f35]], [[8twz]], [[9ngf]], [[9ngg]], [[9ngq]], [[9ngr]], [[9ngs]] - EchELIC – Cryo EM<br />
**[[8d66]], [[8d67]], [[8d68]] – EchELIC3 (mutant) – Cryo EM<br />
**[[8d66]], [[8d67]], [[8vuw]] – EchELIC3 (mutant) – Cryo EM<br />
**[[3rqw]] - EchELIC + acetylcholine<br />
**[[3rqw]] - EchELIC + acetylcholine<br />
**[[5sxu]] - EchELIC + bromoethanol<br />
**[[5sxu]] - EchELIC + bromoethanol<br />
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*ATP-Gated P2X channel (AGC) or P2X purinoceptor
*ATP-Gated P2X channel (AGC) or P2X purinoceptor


**[[9b95]], [[9c2a]], [[9c2c]], [[9lxc]] – hAGC P2X1 + antagonist – Cryo EM<br />
**[[8zt1]], [[8zt2]], [[8zt5]], [[8zt8]], [[8zta]], [[8ztd]], [[8ztf]], [[9b73]], [[9c2b]], [[9lx5]] – hAGC P2X1 + ATP – Cryo EM<br />
**[[9xqr]] – hAGC P2X1 + ATP + antagonist – Cryo EM<br />
**[[9ddv]], [[9ogh]], [[9uww]] – hAGC P2X2 – Cryo EM<br />
**[[9ddw]], [[9ddx]], [[9oir]], [[9ojk]], [[9om0]], [[9omr]], [[9on5]], [[9on6]], [[9uwx]], [[9uwy]] – hAGC P2X2 + ATP – Cryo EM<br />
**[[9z32]] – hAGC P2X2 (mutant) + ATP – Cryo EM<br />
**[[9ohk]] – hAGC P2X2 + suramin – Cryo EM<br />
**[[5svj]], [[5svs]], [[5svt]] – hAGC P2X3 <br />
**[[5svj]], [[5svs]], [[5svt]] – hAGC P2X3 <br />
**[[5yve]] – hAGC P2X3 + modulator<br />
**[[5yve]] – hAGC P2X3 + modulator<br />
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**[[5svm]], [[5svp]] – hAGC P2X3 + agonist<br />
**[[5svm]], [[5svp]] – hAGC P2X3 + agonist<br />
**[[5svk]], [[5svl]], [[6ah4]], [[6ah5]] – hAGC P2X3 + ATP<br />
**[[5svk]], [[5svl]], [[6ah4]], [[6ah5]] – hAGC P2X3 + ATP<br />
**[[9bpd]], [[21dx]] – hAGC P2X3 + ATP – Cryo EM<br />
**[[9ux1]], [[9ux2]] – hAGC P2X2 + P2X3 + ATP – Cryo EM<br />
**[[9ux3]] – hAGC P2X2 + P2X3 + ATP + antagonist – Cryo EM<br />
**[[9ux4]] – hAGC P2X3 + drug – Cryo EM<br />
**[[21fg]] – hAGC P2X3 + ATP + drug – Cryo EM<br />
**[[21fg]] – hAGC P2X3 + ATP + drug – Cryo EM<br />
**[[9ik1]] – hAGC P2X3 + ATP + antagonist – Cryo EM<br />
**[[9bqh]] – hAGC P2X4 – Cryo EM<br />
**[[9bqi]] – hAGC P2X4 + antagonist – Cryo EM<br />
**[[9gp7]] – hAGC P2X4 (mutant) + antagonist – Cryo EM<br />
**[[9c48]] – hAGC P2X4 + ATP – Cryo EM<br />
**[[9e3m]], [[9e3o]], [[9e3p]] – hAGC P2X7 + antagonist – Cryo EM<br />
**[[9e3n]] – hAGC P2X7 + ATP – Cryo EM<br />
**[[5u1l]] – paAGC P2X - panda<br />
**[[5u1l]] – paAGC P2X - panda<br />
**[[5u1u]], [[5u1v]], [[5u1w]], [[5u1x]], [[5u1y]] – paAGC P2X + antagonist <br />
**[[5u1u]], [[5u1v]], [[5u1w]], [[5u1x]], [[5u1y]] – paAGC P2X + antagonist <br />
**[[5u2h]] – paAGC P2X + antagonist + ATP <br />
**[[5u2h]] – paAGC P2X + antagonist + ATP <br />
**[[8jv7]], [[8jv8]], [[8z0z]], [[8z1d]] – paAGC P2X7 + antagonist – Cryo EM<br />
**[[9bpc]] – dAGC P2X3 + drug – dog - Cryo EM<br />
**[[6u9v]] – raAGC P2X7 – Cryo EM<br />
**[[6u9v]] – raAGC P2X7 – Cryo EM<br />
**[[6u9w]] – raAGC P2X7 + ATP – Cryo EM<br />
**[[6u9w]] – raAGC P2X7 + ATP – Cryo EM<br />
**[[8tr5]], [[8v4s]] – raAGC P2X7 + GDP – Cryo EM<br />
**[[8tr6]], [[8tr7]], [[8tr8]], [[8tra]], [[8trb]], [[8trk]] – raAGC P2X7 + antagonist – Cryo EM<br />
**[[8trj]] – raAGC P2X7 + agonist – Cryo EM<br />
**[[2rup]] – raAGC P2X4 head domain 111-167 – NMR<br />
**[[2rup]] – raAGC P2X4 head domain 111-167 – NMR<br />
**[[9e3q]] – mAGC P2X7 + GDP – Cryo EM<br />
**[[5xw6]] – cAGC P2X7 + antagonist<br />
**[[5xw6]] – cAGC P2X7 + antagonist<br />
**[[8jv5]], [[8jv6]] – zeAGC P2X4 (mutant) + inhibitor – zebrafish - Cryo EM<br />
**[[3h9v]], [[3i5d]] – zeAGC P2X4
**[[3h9v]], [[3i5d]] – zeAGC P2X4
**[[4dw0]] – zeAGC P2X4 (mutant)<br />
**[[4dw0]] – zeAGC P2X4 (mutant)<br />
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**[[2eta]], [[2etb]], [[2etc]] – raTRPV2 ankyrin repeat domain <br />
**[[2eta]], [[2etb]], [[2etc]] – raTRPV2 ankyrin repeat domain <br />
**[[6bo4]], [[6bo5]], [[6u84]], [[6u86]] – raTRPV2 – Cryo EM<br />
**[[6bo4]], [[6bo5]], [[6u84]], [[6u86]] – raTRPV2 – Cryo EM<br />
**[[6wkn]], [[7n0m]], [[7n0n]], [[7t37]], [[7t38]], [[7zjh]], [[8fx8]], [[8fxg]], [[8slx]], [[8sly]] – raTRPV2 + cannabidiol – Cryo EM<br />
**[[6wkn]], [[7n0m]], [[7n0n]], [[7t37]], [[7t38]], [[7zjh]], [[8slx]], [[8sly]] – raTRPV2 + cannabidiol – Cryo EM<br />
**[[6u88]], [[6u8a]] – rTRPV2 + cannabidiol – Cryo EM<br />
**[[6u88]], [[6u8a]] – rTRPV2 + cannabidiol – Cryo EM<br />
**[[6bwm]] – rTRPV2 <br />
**[[6bwm]] – rTRPV2 <br />

Latest revision as of 08:51, 24 June 2026

3D structures of ion channels

Updated on 24-June-2026

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

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