TGF beta signaling pathway

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Human hTGFR-II extracellular domain (green) complex with TGF-β3 (grey) (PDB code 1ktz)

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References

  1. Burdette JE, Jeruss JS, Kurley SJ, Lee EJ, Woodruff TK. Activin A mediates growth inhibition and cell cycle arrest through Smads in human breast cancer cells. Cancer Res. 2005 Sep 1;65(17):7968-75. doi: 10.1158/0008-5472.CAN-04-3553. PMID:16140969 doi:http://dx.doi.org/10.1158/0008-5472.CAN-04-3553
  2. Wrana JL. TGF-beta receptors and signalling mechanisms. Miner Electrolyte Metab. 1998;24(2-3):120-30. PMID:9525694

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Alexander Berchansky

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