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Im2 is the Colicin Immunity Protein for Colicin E2, produced by the cell at the same time to protect itself from the DNase Activity of the cytotoxic domain of ColE2. It is released when the Colicin binds to a cell surface receptor of a target cell.

Im2 is also capable of binding to Colicin E9, which has a high level of sequence homology to ColE2, and also inhibit the activity of the cytotoxic domain. This structure shows the binding of to .

Im2 bound to ColE9

Drag the structure with the mouse to rotate

3D structures of colicin-E2 immunitiy protein

Colicin Immunity Protein

Proteopedia Page Contributors and Editors (what is this?)

Gemma McGoldrick, Michal Harel

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