RNaseA Nobel Prizes

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This page, as it appeared on September 29, 2011, was featured in this article in the journal Biochemistry and Molecular Biology Education.

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3D structures of ribonuclease


See Also


  1. 1.0 1.1 Raines RT. Ribonuclease A. Chem Rev. 1998 May 7;98(3):1045-1066. PMID:11848924
  2. 'Anfinsen Nobel Lecture' [1]
  3. 'Anfinsen Nobel Biography' [2]
  4. Anfinsen CB. Principles that govern the folding of protein chains. Science. 1973 Jul 20;181(4096):223-30. PMID:4124164
  5. 5.0 5.1 'Lehninger A., Nelson D.N, & Cox M.M. (2008) Lehninger Principles of Biochemistry. W. H. Freeman, fifth edition.'
  6. 6.0 6.1 6.2 Pearson MA, Karplus PA, Dodge RW, Laity JH, Scheraga HA. Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A. Protein Sci. 1998 May;7(5):1255-8. PMID:9605332 doi:10.1002/pro.5560070522
  7. Schultz DA, Friedman AM, White MA, Fox RO. The crystal structure of the cis-proline to glycine variant (P114G) of ribonuclease A. Protein Sci. 2005 Nov;14(11):2862-70. Epub 2005 Sep 30. PMID:16199662 doi:10.1110/ps.051610505
  8. Hogan, Dan. ed. Dysfunctional Protein Dynamics Behind Neurological Disease? ScienceDaily.2 Nov. 2009. www.sciencedaily.com [3]
  9. 9.0 9.1 9.2 9.3 Merrifield B. "Solid Phase Synthesis", Nobel Lecture, 8 December, 1984.
  10. 10.0 10.1 10.2 10.3 Martin PD, Doscher MS, Edwards BF. The refined crystal structure of a fully active semisynthetic ribonuclease at 1.8-A resolution. J Biol Chem. 1987 Nov 25;262(33):15930-8. PMID:3680234
  11. 11.0 11.1 11.2 11.3 11.4 11.5 Boerema DJ, Tereshko VA, Kent SB. Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A. Biopolymers. 2008;90(3):278-86. PMID:17610259 doi:10.1002/bip.20800
  12. Doscher MS, Martin PD, Edwards BF. Characterization of the histidine proton nuclear magnetic resonances of a semisynthetic ribonuclease. Biochemistry. 1983 Aug 16;22(17):4125-31. PMID:6615822
  13. Lin MC. The structural roles of amino acid residues near the carboxyl terminus of bovine pancreatic ribonuclease A. J Biol Chem. 1970 Dec 25;245(24):6726-31. PMID:4921569

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