DNA polymerase 3D structures

3D Structures of DNA polymerase

Updated on 06-July-2021

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• DNA polymerase I
  • 1taq – TaDpo I - Thermus aquaticus
    
  • 1jxe – TaDpo I Stoffel fragment 290-832
    
  • 5ktq – TaDpo I Stoffel fragment + nucleotide
    
  • 5szt, 5e41, 6q4v, 6q4u, 6fbi, 6fbh, 6fbg, 6fbf, 6fbe, 6fbd, 6fbc, 5z3n, 5yth, 5ytg, 5ytf, 5yte, 5ytd, 5ytc, 5w6k, 5w6q – TaDpo I Stoffel fragment + DNA + nucleotide derivative
    
  • 5nkl – TaDpo I + DNA + pyridine derivative + pyrrol derivative
    
  • 5o7t – TaDpo I (mutant) + DNA + CTP derivative
    
  • 5oxj – TaDpo I + DNA + GMP derivative + imidazole derivative
    
  • 3ojs, 3oju, 1tau, 4dle, 4dlg, 4elt, 4elu, 4elv - TaDpo I + DNA
    
  • 4flt, 4flu, 4flv, 4flw, 4flx, 4fly, 4flz, 4fm0, 4fm1, 4fm2 – Dpo I + DNA – Pyrococcus abyssi
    
  • 1s5j – SsDpo I - Sulfolobus solfataricus
    
  • 6dsy, 6dsx, 6dsw, 6dsv, 6dsu, 7k5o, 7k5p, 7k5r, 7k5s, 7k5u - GsDpo I + DNA - Geobacillus stearothermophilus
    
  • 3eyz, 6p5c - GsDpo I (mutant) + DNA
    
  • 6mu5, 6mu4, 6ur2, 6ur4 - GsDpo I + DNA + nucleotide derivative
    
  • 3eyz - GsDpo I (mutant) + DNA
    
  • 3ez5, 6ueu, 6ur9, 6us5 - GsDpo I (mutant) + DNA + nucleotide 
    
  • 3pv8, 3px0, 3px4, 3px6, 4dqi, 4dqp, 4dqq, 4dqr, 4dqs, 4ds4, 4ds5, 4dse, 4dsf, 4e0d, 4ez6, 4ez9, 4f2r, 4f2s, 4f3o, 4f4k, 4f8r - GkDpo I (mutant) + DNA – Geobacillus kaustophilus
    
  • 6vdc, 6vde – MsPol I – Mycobacterium smegmatis
    
  • 6vdd - MsDpo I + DNA + nucleotide derivative
    
• DNA polymerase I klenow fragment
  • 2kzz, 1d8y, 2kzm – EcDpo I - Escherichia coli
    
  • 1qsl - EcDpo I + DNA
    
  • 1kfd, 1dpi - EcDpo I + nucleotide
    
  • 1d9d, 1d9f, 2kfn - EcDpo I + DNA + nucleotide
    
  • 1ktq - TaDpo I
    
  • 3po4, 3po5, 3rtv, 3sv3, 3sv4, 3syz, 3sz2, 4c8k, 4c8l, 4c8m, 4c8n, 4c8o, 4cch - TaDpo I + DNA
    
  • 4bwm, 4bwj - TaDpo I + DNA + RNA
    
  • 2xo7, 3hp6, 3hpo, 2hhq, 2hhs, 2hht, 2hhu, 2hhv, 2hhw, 2hhx, 2hvh, 2hvi, 2hw3, 1xc9, 1ua0, 1ua1, 1njw, 1njx, 1njy, 1njz, 1nk0, 1nk4, 1nk5, 1nk6, 1nk7, 1nk8, 1nk9, 1nkb, 1nkc, 1nke, 1l3s, 2bdp, 4bdp, 2xy5, 2xy6, 2xy7, 2y1i, 2y1j, 3tan, 3tap, 3taq, 3tar, 3thv, 4b9l, 4b9m, 4b9n, 4b9s, 4b9t, 4b9u, 4b9v - GsDpo I + DNA
    
  • 4dsi, 4dsj, 4dsk, 4dsl, 4dwi - GsDpo I (mutant) + DNA
    
  • 3ht3, 1u45, 1u47, 1u48, 1u49, 1u4b, 1l3t, 1l3u, 1l3v, 1l5u, 1lv5, 3bdp, 3ti0, 4o0i, 4uqg - GsDpo I + DNA + nucleotide
    
• DNA polymerase II
  • 3maq, 3k57, 3k58, 3k59, 3k5l, 3k5m - EcDpo II (mutant) + DNA + nucleotide
    
  • 3k5n - EcDpo II (mutant) + DNA
    
  • 3k5o, 1q8i - EcDpo II (mutant)
    
  • 3o59 - PhDpo II large subunit]] - Pyrococcus horikoshii
    
  • 2kxe - PhDpo II small subunit
    
  • 5ijl - PaDpo II large subunit
    
  • 5ihe - PaDpo II small subunit
    
  • 6hmf - PaDpo II small subunit (mutant)
    
  • 6hms - PaDpo II small+large subunits + DNA – Cryo EM
    
  • 6knb, 6knc - TkPol II small+large subunits + PCNA + DNA - Thermococcus kodakarensis – Cryo EM
    
• DNA polymerase III subunit α
  • 2hnh, 2hqa - EcDpo III subunit α catalytic fragment
    
  • 2hpi, 2hpm - TaDpo III α subunit
    
  • 3e0d - TaDpo III α subunit + DNA
    
  • 3f2b, 3f2c, 3f2d, 4iqj – GkDpo III α subunit + DNA + nucleotide
    
  • 5m1s, 5fkw, 5fkv, 5fku - EcDpo III α(mutant)β,ε subunits + DNA – Cryo EM
    
  • 1ok7 - EcDpo III residues 1-366 + EcDpo IV C-terminal
    
  • 1zd7, 1zde, 3nzm, 5ol5, 5ol1 - SyDpo III α subunit – Synechocystis
    
  • 4gig - SyDpo III α subunit (mutant)
    
  • 2keq, 4kl5, 4kl6 - NpDpo III α subunit – Nostoc punctiforme
    
  • 4lx3, 4qfq - NpDpo III α subunit + nucleic acid binding tRNA/helicase
    
  • 5lew - MtPol III α subunit – Mycobacterrium tuberculosis
    
• DNA polymerase III subunit β or sliding clamp
  • 2pol, 4k3s, 4pnv, 4pnw - EcDpo III subunit β
    
  • 2xur, 3f1v, 3pwe - EcDpo III subunit β (mutant)
    
  • 2avt - Dpo III β subunit – Streptococcus pyogenes
    
  • 2awa - Dpo III β subunit – Streptococcus pneumoniae
    
  • 4trt – DrDpo III β subunit – Deinococcus radiodurans
    
  • 2p1j – TmDpo III exonuclease domain – Thermotoga maritima
    
  • 1vpk - TmDpo III β subunit
    
  • 3t0p - Dpo III β subunit – Eubacterium rectale
    
  • 6ap4 - Dpo III β subunit – Acinetobacter baumannii
    
  • 6amq - Dpo III β subunit – Enterobacter cloacae
    
  • 5wyp, 5wce, 6izo, 6jir - Dpo III β subunit – Caulobacter crescentus
    
  • 5w7z - RcDpo III β subunit – Rickettsia conorii
    
  • 6man - Dpo III β subunit – Rickettsia bellii
    
  • 6d46 - RtDpo III β subunit – Rickettsia typhi
    
  • 6dlk - Dpo III  subunit – Rickettsia rickettsii
    
  • 6d47 - Dpo III  subunit – Mycobacterium marinum
    
  • 1jqj, 1jql - EcDpo III subunit β,γ(mutant)
    
  • 4tr6 - Pol III β subunit – Bacillus subtilis
    
  • 3p16, 3rb9, 4tr7 - MtPol III β subunit
    
  • 4tr8, 6ams - PsaPol III β subunit – Pseudomonas aeruginosa
    
  • 6pth - PsaPol III β subunit + griselimycin
    
  • 4s3i, 4rki - HpPol III β subunit – Helicobacter pylori
    
  • 6aig - Dpo III β subunit – Aeropyrum pernix
    
  • 6deg - Dpo III  subunit – Bartonella birtlesii
    
• DNA polymerase III subunit beta or sliding clamp complex
  • 3d1g, 3qsb, 4k3k, 4k3l, 4mjp, 4mjq, 4mjr, 4n94, 4n95, 4n96, 4n97, 4n98, 4n99, 4n9a, 4ovf, 4ovg, 4ovh, 4pnu - EcDpo III subunit β + inhibitor
    
  • 3bep - EcDpo III subunit β + DNA
    
  • 5x06 - EcDpo III subunit β + DnaA regulatory inactivator
    
  • 3d1f, 3q4j, 3q4k, 3q4l, 4k3l, 4k3m, 4k3o, 4k3p, 4k3q, 4k3r, 4k74, 6fvl - EcDpo III β subunit + polypeptide
    
  • 6fvm - EcDpo III β subunit (mutant) + P7 peptide
    
  • 5g4q, 5g48, 5fxt, 5fve - HpPol III β subunit + NSAID drug
    
  • 5frq - HpPol III β subunit + DNA ligase peptide
    
  • 5dai - TkPol III β subunit + FEN-1 peptide - Thermococcus kodakarensis
    
  • 5ah4, 5ah2, 5agv, 5agu – MsPol III β subunit + gricelimycin – Mycobacterium smegmatis
    
  • 6drt – T4Dpo III β subunit + polypeptide - Enterobacteria phage T4
    
  • 6dj8 – Dpo III β subunit + polypeptide – Borrelia burgdorferi
    
  • 6fvo, 6fvn - MtPol III β subunit + P7 peptide
    
  • 6t7x - PaPol III β subunit
    
  • 4tsz, 6t7y - PaPol III β subunit + peptide
    
  • 6t8h - PaPol III β subunit + Dol II small subunit + DP2 – Cryo EM
    
  • 6djk - RtDpo III β subunit + polypeptide
    
  • 6dm6 - RcPol III β subunit + peptide
    
• DNA polymerase III subunit γ
  • 1njf, 1njg - EcDpo III subunit γ N-terminal domains 1-2
    
  • 2gno - TmDpo III γ subunit
    
  • 1xxh, 1jr3 - EcDpo III subunit γ,δ,δ’
    
  • 1xxi - EcDpo III subunit γ,δ,δ’ + nucleotide
    
• DNA polymerase III subunit δ
  • 1a5t - EcDpo III subunit δ’
    
  • 1xxh, 1jr3 - EcDpo III subunit γ,δ,δ’
    
  • 1xxi - EcDpo III subunit γ,δ,δ’ + nucleotide
    
  • 3glh - EcDpo III subunit δ,δ’,τ
    
  • 3glf - EcDpo III subunit δ,δ’,τ + DNA
    
  • 3gli - EcDpo III subunit δ,δ’,τ,ξ + DNA
    
• DNA polymerase III subunit ε
  • 2gui – EcDpo III subunit ε N-terminal
    
  • 1j53, 1j54 - EcDpo III subunit ε N-terminal exonuclease domain
    
  • 2ido - EcDpo III subunit ε + HOT protein
    
  • 4gx8 - EcDpo III ε subunit/ EcDpo III α subunit
    
  • 2xy8 - EcDpo III subunit ε,θ
    
• DNA polymerase III subunit τ
  • 2aya - EcDpo III subunit τ
    
  • 3glh - EcDpo III subunit δ,δ’,τ
    
  • 3glf - EcDpo III subunit δ,δ’,τ + DNA
    
• DNA polymerase III subunit xi
  • 3gli - EcDpo III subunit δ,δ’,τ,ξ + DNA
    
• DNA polymerase III subunit θ
  • 2xy8 - EcDpo III subunit ε,θ
    
  • 2axd, 2ae9, 1du2 - EcDpo III subunit θ - NMR
    
• DNA polymerase III subunit χ
  • 1em8 - EcDpo III subunit ϕ,χ
    
  • 3sxu - EcDpo III subunit ϕ,χ + peptide
    
• DNA polymerase III subunit φ
  • 1em8 - EcDpo III subunit ϕ,χ
    
  • 3sxu - EcDpo III subunit ϕ,χ + peptide
    
• DNA polymerase IV
  • 4ir1, 4ir9, 4irc, 4ird, 4irk, 5zlv, 5yye, 5yyd, 5yv3, 5yv2, 5yv1, 5yv0, 5yuz, 5yuy, 5yux, 5yuw, 5yuv, 5yuu, 5yut, 5yus, 5yur - EcPol IV + DNA
    
  • 4r8u, 5c5j, 4q45, 4q44, 4q43, 6ig1 - EcPol IV + DNA + nucleotide
    
  • 6jup, 6juq - EcPol IV (mutant) + DNA + nucleotide
    
  • 2rdi - SsPol IV
    
  • 1s9f, 1s97, 1s0m, 1s0n, 1s0o, 1s10, 1n48, 1n56, 1jx4, 1jxl, 2xca, 2xcp, 2w8k, 2w8l, 2rdj, 2v9w, 2va2, 2va3, 2ia6, 2ibk, 2jef, 2jeg, 2jei, 2jej, 2imw, 2j6s, 2j6t, 2j6u, 2asd, 2asj, 2asl, 2atl, 2au0, 2c22, 2c28, 2c2d, 2c2e, 2c2r, 2agp, 2agq, 2bqr, 2bqu, 2br0, 2bq3, 3khg, 3khh, 3khl, 3khr, 3t5h, 3t5j, 3t5k, 3t5l, 3v6h, 3v6j, 3v6k, 4gc6, 4gc7, 4juz, 4jv0, 4jv1, 4jv2, 4qw8, 4qw9, 4qwa, 4qwb, 4qwc, 4qwd, 4qwe, 4ruc, 4rua, 4tqr, 4tqs, 5edw, 6vgm - SsPol IV + DNA + nucleotide
    
  • 3pr4, 3pr5, 2r8g, 2r8h, 2r8i, 2uvr, 2uvu, 2uvv, 2uvw - SsPol IV (mutant) + DNA + nucleotide
    
  • 4juz, 4jv0, 4jv1, 4jv2, 4qw8, 4qw9, 4qwa, 4qwb, 4qwc, 4qwd, 4qwe, 4tqr, 4tqs - SsPol IV + DNA + nucleotide
    
  • 2xc9, 3m9m, 3m9n, 3m9o, 2v4q, 2v4r, 2ago, 1ryr, 1rys, 2w9a, 2w9b, 2w9c, 3gii, 3gij, 3gik, 3gil, 3gim, 3qz7, 3qz8, 3pvx, 3pw0, 3pw2, 3pw4, 3pw5, 3pw7, 3raq, 3rax, 3rb0, 3rb3, 3rb4, 3rb6, 3rbd, 3rbe, 4hyk, 4fbt, 4fbu, 4g3i, 4rzr, 6l84, 6l97 - SsPol IV + DNA
    
  • 3fds – SsPol IV + PCNA B + PCNA C
    
  • 3bq2, 3bq0 – SaPol IV + DNA – Sulfolobus acidocaldarius
    
  • 3bq1, 4f4w, 4f4x, 4f4y, 4f4z, 4f50 - SaPol IV + DNA + nucleotide
    
  • 4nlg - SaPol IV (mutant) + DNA
    
  • 4dez – MsPol IV
    
  • 6jul – MsPol IV + DNA
    
  • 6jum, 6jun, 6juo – MsPol IV (mutant) + DNA
    
  • 6jus - MsPol IV + DNA + nucleotide
    
  • 6jur - MsPol IV (mutant) + DNA + nucleotide
    
• DNA polymerase from enterobacteria phage T7
  • 1zyq, 1x9m, 1x9s, 1x9w, 1tk0, 1skr, 1sks, 1skw, 1sl0, 1sl1, 1sl2, 1t7p, 6n2w - T7Dpo (mutant) + thioredoxin + DNA + nucleotide
    
  • 1t8e, 1tk5, 1tk8, 1tkd - T7Dpo + thioredoxin + DNA + nucleotide
    
  • 6n9x, 6n9w, 6n9v - T7Dpo + Gp4 + DNA + nucleotide derivative
    
  • 6n9u - T7Dpo + Gp4 + DNA + RNA + nucleotide derivative
    
  • 5ikn - T7Dpo + thioredoxin + DNA primase/helicase
    
• DNA polymerase
  • 2gv9 – HsvDpo – Herpes simplex virus
    
  • 7luf – HsvDpo + DNA
    
  • 5n2g, 5n2e – VvDpo – Vaccinia virus
    
  • 5n2h – VvDpo (mutant)
    
  • 5mdn – Dpo – Pyrobaculum calidifontis
    
  • 1bgx – TaDpo + TP7 antibody
    
  • 1ih7 – EpDpo]] - Enterobacteria phage RB69
    
  • 1waf, 1waj - EpDpo + nucleotide
    
  • 3uiq, 4dtj, 4dtm, 4dtn, 4dto, 4dtp, 4dtr, 4dts, 4dtu, 4dtx, 4du1, 4du3, 4du4 - EpDpo + DNA
    
  • 3nci, 3lds, 3l8b, 3cq8, 3cfp, 3cfr, 3kd1, 3kd5, 4e3s - EpDpo (mutant) + DNA
    
  • 3ndk, 3ne6, 3ngi, 3nhg, 3nae, 3lzj, 3lzi, 2ozs, 2p5g, 2dy4, 1q9x, 1q9y, 1ig9, 3qep, 3rma, 3rmb, 3rmc, 3rmd, 3rwu, 3s9h, 3scx, 3si6, 3sjj, 3snn, 3spy, 3spz, 3sq0, 3sq1, 3sq2, 3sq4, 3sun, 3suo, 3sup, 3suq, 3tab, 3tae, 3taf, 3tag, 4i9q, 4j2a, 4j2b, 4j2d, 4j2e, 4khn, 4khq, 4khs, 4khu, 4khw, 4khy, 4ki4, 4ki6, 4m3r, 4m3t, 4m3u, 4m3w, 4m3x, 4m3y, 4m3z, 4m41, 4m42, 4m45, 5gnq - EpDpo (mutant) + DNA + nucleotide
    
  • 1clq, 3iuq - EpDpo + DNA + nucleotide
    
  • 2oyq, 2ozm, 2p5o, 2dtu, 3qei, 3qer, 3qes, 3qet, 3qev, 3qew, 3qex, 3qnn, 3qno, 4fj5, 4fj7, 4fj8, 4fj9, 4fjg, 4fjh, 4fji, 4fjj, 4fjk, 4fjl, 4fjm, 4fjn, 4fjx, 4fk0, 4fk2, 4fk4 - EpDpo (mutant) + DNA + nucleotide analog
    
  • 2atq – EpDpo + GP32
    
  • 1noy – T4Dpo + DNA - Enterobacteria phage T4
    
  • 1noz – T4Dpo residues 1-388
    
  • 2ex3 – BpDpo (mutant) + DNA terminal protein – Bacillus phage 29
    
  • 2py5, 2pzs, 1xhz, 1xi1 – BpDpo (mutant) + DNA
    
  • 2pyj, 2pyl - BpDpo (mutant) + DNA + nucleotide
    
  • 1xhx - BpDpo (mutant)
    
  • 3a2f - PfDpo + PCNA - Pyrococcus furiosus
    
  • 2jgu, 4ahc – PfDpo
    
  • 4ail – PfDpo + DNA
    
  • 1tgo - TgDpo – Thermococcus gorgonarius
    
  • 2vwk - TgDpo (mutant)
    
  • 7b0h – TgDpo + DNA
    
  • 2vwj, 2xhb – TgDpo (mutant) + DNA
    
  • 1wn7, 1wns, 5vu5 – TkDpo B
    
  • 5vu9, 5vu8, 5vu7, 5vu6, 5omf - TkDpo + DNA
    
  • 4k8z - TkDpo (mutant) + DNA
    
  • 6q4t - TkDpo (mutant) + DNA + nucleotide derivative
    
  • 1qht - ThDpo (mutant) – Thermococcus
    
  • 4k8x, 5omv, 5omq, 6is7, 6isf, 6isg, 6ish, 6isi - ThDpo (mutant) + DNA
    
  • 4yfu - Dpo (mutant) + DNA - Bacillus
    
  • 1d5a – DeDpo
    
• DNA polymerase α
  • 4e2i – hDpo α subunit β + large T antigen – human
    
  • 4y97 - hDpo α catalytic+B subunits
    
  • 5iud - hDpo α catalytic subunit + DNA
    
  • 6as7 - hDpo α catalytic subunit (mutant) + DNA
    
  • 4bpx - hDpo α catalytic subunit + DNA primase small subunit
    
  • 5exr - hDpo α catalytic+B subunits + DNA primase small+large subunits
    
  • 4q5v - hDpo α catalytic subunit + DNA + RNA + aphidicolin
    
  • 4qcl - hDpo α catalytic subunit + DNA + RNA + nucleotide
    
  • 2keb - hDpo αB - NMR
    
  • 1n5g, 1k0p, 1k18 - hDpo α zinc finger domain – NMR
    
• DNA polymerase β
  • 4ppx - hDpo β + spiroiminohydantoin + DNA
    
  • 1zjm, 1tv9, 1tva, 1bpx, 1bpz, 1zqa, 1zqb, 1zqc, 1zqd, 1zqf, 1zqg, 1zqh, 1zqi, 1zaj, 1zqk, 1zql, 1zqm, 1zqn, 1zqo, 1zqp, 1zqq, 1zqr, 1zqs, 1zqt, 1zqu, 1zqv, 1zqw, 1zqx, 1zqy, 1zqz, 1zqe, 3q8p, 3q8q, 3lk9, 3mby, 3isb, 3isc, 3gdx, 3rh4, 3rh5, 3rh6, 4gxi, 4gxj, 4gxk, 4kld, 4kle, 4klf, 4klg, 4klh, 4kli, 4klj, 4kll, 4klm, 4klo, 4klp, 4klq, 4kls, 4klt, 4klu, 1zqj, 4lvs, 4m2y, 4m47, 4nlk, 4nln, 4nlz, 4nm1, 4nm2, 4pgy, 4tup, 4tuq, 4tur, 4tus, 5wo0, 5wnz, 5wny, 5wnx, 5vs4, 5vs3, 5vs2, 5vs1, 5vs0, 5vrz, 5vry, 5vrx, 5vrw, 5vez, 5v1r, 5v1p, 5v1o, 5v1n, 5v1j, 5v1i, 5v1h, 5v1g, 5v1f, 5ugp, 5ugo, 5ugn, 5u9h, 5u8i, 5u8h, 5u8g, 5u2t, 5u2s, 5u2r, 5tzv, 5tbc, 5tbb, 5tba, 5tb9, 5tb8, 5j2k, 5j2j, 5j2i, 5j2h, 5j2g, 5j2f, 5j2e, 5j2d, 5j2c, 5j2b, 5j2a, 5j29, 5j0y, 5j0x, 5j0w, 5j0u, 5j0t, 5j0s, 5j0r, 5j0q, 5j0p, 5j0o, 5dbc, 5dbb, 5dba, 5db9, 5db8, 5db7, 5db6, 6g2q, 6ph5, 7ice, 7icf, 7ici, 7icj, 7icl, 7icm, 7icp, 7icr, 7ict, 7icg, 7ich, 7icj, 7ick, 7icm, 7icn, 7ico, 7icp, 7icq, 7icr, 7ics, 7ict, 7icu, 7icv, 7k97, 8icb, 8icc, 9icj, 9ick, 9icl, 9icm, 9icp, 9icw, 9icx, 9icy - hDpo  + DNA
    
  • 1bpy, 1mq2, 1mq3, 1zjn1, 2pxi, 2iso, 2isp, 2i9g, 2fmp, 2fmq, 2fms, 3jpn, 3jpo, 3jpp, 3jpq, 3jpr, 3jpt, 3jps, 3isd, 3c2k, 3c2l, 3c2m, 3rje, 3rjf, 3rjg, 3rjh, 3rji, 3rjj, 3rjk, 3tfr, 3tfs, 4do9, 4doa, 4dob, 4doc, 4mf2, 4mf8, 4mfa, 4mfc, 4mff, 4nxz, 4ny8, 4o5c, 4o5e, 4o5k, 4o9m, 4p2h, 4pgq, 4pgx, 4pha, 4phd, 4uaw, 4uay, 4uaz, 4ub1, 4ub2, 4ub3, 4ub4, 4ub5, 4ubb, 4ubc, 4z6f, 4z6e, 4z6d, 4z6c, 4yn4, 4ymo, 4ymn, 4ymm, 4rt3, 4rt2, 4rq8, 4rq7, 4rq6, 4rq5, 4rq4, 4rq3, 4rq2, 4rq1, 4rq0, 4rpz, 4rpy, 4rpx, 4php, 4phe, 4ph5, 5eoz, 5bpc, 5bom, 5bol, 8ica, 8ice, 8icf, 8icg, 8ich, 8ici, 8icj, 8ick, 8icl, 8icm, 8icn, 8ico, 8icp, 8icq, 8icr, 8ics, 8ict, 8icu, 8icv, 8icw, 8icx, 8icy, 8icz, 9ica, 9icb, 9icc, 9ice, 9icf, 9icg, 9ich, 9ici, 9icn, 9ico 9icq, 9icr, 9ics, 9ict, 9icu, 9icv - hDpo  + DNA + nucleotide
    
  • 2p66, 4f5n, 6n2t, 6n2s, 6n2r, 6mr8, 6mr7, 6e3x, 6e3w, 6e3v, 6e3r, 6dia, 6cub, 6cua, 6cu9, 6ctx, 6ctw, 6ctv, 6ctu, 6ctt, 6ctr,

6ctq, 6ctp, 6cto, 6ctn, 6ctm, 6ctl, 6ctk, 6ctj, 6cti, 6crh, 6crc, 6crb, 6cr9, 6cr8, 6cr7, 6cr6, 6cr5, 6cr4, 6cr3, 6cpq, 6cly, 6bem, 6bel, 6ph6, 6u2o, 6u6b, 6uok, 6uol, 6uom, 7k96 - hDpo  + DNA + nucleotide analog

• • 4f5o, 4f5p, 4f5q, 4f5r, 6n2t, 6n2s, 6n2r, 6mr8, 6mr7, 6e3x, 6e3w, 6e3v, 6e3r, 6dia, 6cub, 6cua, 6cu9, 6ctx, 6ctw, 6ctv, 6ctu, 6ctt, 6ctr, 6ctq, 6ctp, 6cto, 6ctn, 6ctm, 6ctl, 6ctk, 6ctj, 6cti, 6crh, 6crc, 6crb, 6cr9, 6cr8, 6cr7, 6cr6, 6cr5, 6cr4, 6cr3, 6cpq, 6cly, 6bem, 6bel, 6dic, 6btf, 6bte, 6nkr, 6nks, 6nkt, 6nku, 6nkv, 6nkw, 6nkx, 6nky, 6nkz, 6nl0, 6pkz - hDpo β (mutant) + DNA + nucleotide analog
    
  • 3ogu, 4jwm, 4jwn, 4m9g, 4m9h, 4m9j, 4m9l, 4m9n, 4r63, 4r64, 4r65, 4r66 - hDpo β (mutant) + DNA
    
  • 5hhi, 5hhh - hDpo β + DNA + azanide derivative
    
  • 2v6z - hDpo β N-terminal (mutant)]] - NMR
    
  • 3k75, 3lqc - hDpo β + DNA repair protein XRCC1
    
  • 1rpl, 2bpc, 1bpe, 1bpb, 1bpd, 3uxn - rDpo β – rat
    
  • 2van, 1jn3, 3uxo, 3v7l- rDpo β (mutant)
    
  • 1dk2, 1dk3, 1bno, 1bnp - rDpo β N-terminal – NMR
    
  • 1nom - rDpo β C-terminal
    
  • 1huo, 1huz, 3v7j - rDpo β + DNA
    
  • 3uxp, 3v72, 3v7k - rDpo β (mutant) + DNA
    
  • 1bpe - rDpo β + nucleotide
    
  • 2bpf, 2bpg - rDpo β + DNA + nucleotide
    
  • 3au2 – TtDpo β + GTP – Thermus thermophilus
    
  • 3b0x, 3b0y – TtDpo β (mutant) + GTP
    
  • 3au6, 3auo – TtDpo β + GTP + DNA
    β
  • 4p4m, 4p4o, 4p4p - Dpo β + DNA + nucleotide – Leishmania infantum
    
• DNA polymerase γ
  • 3ikm - hDpo γ1+ γ2
    
  • 3ikl, 2g4c - hDpo γ2
    
  • 2jw5 - hDpo λ BRCT domain
    
  • 1xsl - hDpo λ catalytic domain
    
  • 1nzp - hDpo λ lyase domain - NMR
    
  • 3pmn, 3pnc, 3mda, 2gws, 2bcq, 2bcr, 2bcs, 2bcu, 2bcv, 1xsp, 1rzt - hDpo λ + DNA
    
  • 3mgh, 3c5f, 3c5g, 2pfn - hDpo λ (mutant) + DNA
    
  • 3pml, 3mdc, 1xsn - hDpo λ + DNA + nucleotide
    
  • 4k4g, 4k4h, 4k4i - hDpo λ + DNA + nucleotide analog
    
  • 3mgi, 3hw8, 3hwt, 3hx0, 2pfo, 2pfp, 2pfq - hDpo λ (mutant) + DNA + nucleotide
    
• DNA polymerase δ
  • 3e0j - hDpo δ2+ δ3
    
  • 3upq, 3uq0, 3uq2 - hDpo δ (mutant) + DNA
    
  • 4fo6 - hDpo δ (mutant) + DNA + nucleotide analog
    
  • 6s1m, 6s1n, 6s1o, 6tny - hDpo δ subunits catalytic+2+3+4 + PCNA + DNA + nucleotide analog – Cryo EM
    
  • 6tnz - hDpo δ subunits catalytic+2+3+4 + PCNA + FLAP endonuclease +DNA + nucleotide analog – Cryo EM
    
  • 7kc0 - hDpo δ + PCNA + POL31 + POL32 +DNA + nucleotide analog – Cryo EM
    
• DNA polymerase ε
  • 5vbn - hDpo ε subunits A+2
    
• DNA polymerase ζ
  • 3abd, 3abe - hDpo ζ catalytic subunit Rev3 + mitotic spindle assembly checkpoint protein Rev7
    
  • 6ekm, 6bi7, 6bcd, 6bc8 - hDpo ζ catalytic subunit + MAD2B
    
  • 3vu7, 4gk0, 6ws0 - hDpo ζ catalytic subunit + DNA repair protein Rev1 + MAD2B
    
  • 6ws5 - hDpo ζ catalytic subunit + DNA repair protein Rev1 + MAD2B + inhibitor
    
  • 4fjo, 4gk5 - hDpo κ + hDpo ζ catalytic subunit + DNA repair protein Rev1 + MAD2B
    
  • 6v8p - hDpo ζ catalytic subunit + hDpo d subunits 3+small – Cryo EM
    
  • 6v93 - hDpo ζ catalytic+processivity subunits + hDpo d subunits 3+small + DNA + dCTP – Cryo EM
    
• DNA polymerase η
  • 2i5o - hDpo η ubiquitin-binding zinc finger – NMR
    
  • 2lsj, 2lsi - hDpo η + DNA repair protein Rev1
    
  • 6mp3 - hDpo η + DNA
    
  • 4dl2, 4dl3, 4dl4, 4dl5, 4dl6, 4dl7, 4eey, 4ecq, 4ecr, 4ecs, 4ect, 4ecu, 4ecv, 4ecw, 4ecx, 4ecy, 4ecz, 4ed0, 4ed1, 4ed2, 4ed3, 4ed6, 4ed7, 4ed8, 4o3n, 4o3o, 4o3p, 4o3q, 4o3r, 4o3s, 4q8e, 4q8f, 4rnm, 4rnn, 4rno, 3mr2, 3mr3, 3mr5, 3mr6, 3si8, 3mr2, 3mr3, 3mr5, 3mr6, 5l9x, 5l1l, 5l1k, 5l1j, 5l1i, 5kg7, 5kg6, 5kg5, 5kg4, 5kg3, 5kg2, 5kg1, 5kg0, 5kfz, 5kfy, 5kfx, 5kfw, 5kfv, 5kfu, 5kft, 5kfs, 5kfr, 5kfq, 5kfp, 5kfo, 5kfn, 5kfm, 5kfl, 5kfk, 5kfj, 5kfi, 5kfh, 5kfg, 5kff, 5kfe, 5kfd, 5kfc, 5kfb, 5kfa, 5jum, 5f9n, 5f9l, 5ewg, 5ewf, 5ewe, 5dqi, 5dqh, 5dqg, 5dlg, 5dlf, 5dgb, 5dga, 5dg9, 5dg8, 5dg7, 4yr3, 4yr2, 4yr0, 4yqw, 4yp3, 4ru9, 6mxo, 6m7v, 6m7u, 6m7t, 6m7p, 6m7o, 6d0z, 6d0m, 6mq8, 6pl7, 6pl8, 6plc, 6ui2, 6uqi, 6v5k, 6wk6 - hDpo η + DNA + nucleotide
    
  • 6pz3, 6q02 - hDpo η (mutant) + DNA + nucleotide
    
  • 5aga - hDpo η + nucleotide
    
• DNA polymerase ι
  • 3q8r, 3q8s, 3h4b, 3h4d, 3gv5, 3gv7, 3gv8, 3epg, 3epi, 2fll, 2fln, 2flp, 2dpi, 2dpj, 2alz, 1zet, 1t3n, 4ebc, 4ebd, 4ebe, 4fs1, 4fs2, 4eyh, 4eyi, 3g6v, 3g6x, 3g6y, 5ulx, 5ulw, 5kt7, 5kt6, 5kt5, 5kt4, 5kt3, 5kt2 - hDpo ι + DNA + nucleotide
    
  • 3ngd, 3osn, 3h40, 5ulx, 5ulw - hDpo ι catalytic fragment + DNA
    
  • 2ktf - hDpo ι + ubiquitin
    
  • 2l0f, 2l0g - hDpo ι + ubiquitin – NMR
    
  • 2khu - hDpo ι ubiquitin binding motif – NMR
    
  • 2khw - hDpo ι ubiquitin binding motif + ubiquitin – NMR
    
  • 2kwu, 2kwv - mDpo ι C-terminal + ubiquitin - NMR
    
  • 3ai4 - mDpo ι/yEGFP
    
• DNA polymerase κ
  • 1t94 - hDpo κ
    
  • 3in5 - hDpo κ + DNA
    
  • 2w7o, 2w7p, 2oh2, 3pzp, 6cst, 6bs1, 6brx, 5w2a, 5w2c - hDpo κ + DNA + nucleotide
    
  • 2lsi - hDpo κ peptide + hRev1
    
  • 2lsk - mDpo κ + DNA repair protein Rev1
    
• DNA polymerase λ
  • 5cb1 – hDpo
    
  • 5iio, 5iin, 5iim, 5iil, 5iik, 5iij, 5iii, 5ddm – hDpo + DNA
    
  • 5cp2 – hDpo (mutant) + DNA
    
  • 5dkw, 5ca7, 4xus, 4xrh, 4xq8, 4xa5, 4x5v – hDpo + DNA + nucleotide
    
  • 5cwr, 5cr0, 5cj7, 5chg – hDpo (mutant) + DNA + nucleotide
    
  • 5ddy – hDpo + nucleotide
    
• DNA polymerase μ
  • 2htf, 2dun - hDpo μ BRCT domain – NMR
    
  • 5tyx, 5tyw, 5tyv, 5tyu, 5tyg, 5tyf, 5tye, 5tyd, 5tyc, 5tyb, 5txz, 5txx, 5tws, 5twr, 5twq, 5twp - hDpo  residues 132-494 + DNA
    
  • 4yd2, 4ycx - hDpo μ residues 132-494 (mutant) + DNA
    
  • 6ak5 - hDpo μ residues 132-397+411-494 + nucleotide derivative
    
  • 6ipn, 6ipm, 6ipl, 6ipk, 6ipj, 6ipi, 6iph, 6aec, 6aeh, 6ak6 - hDpo μ residues 132-397+411-494 (mutant) + nucleotide derivative
    
  • 7coa - hDpo μ + DNA + nucleotide derivative
    
  • 4yd1, 6ipg, 6ipf, 6ipe, 6ipd, 5vz7, 5vz8, 5vz9, 5vza, 5vzb, 5vzc, 5vzd, 5vze, 5vzf, 5vzg, 5vzh, 5vzi, 6ak8, 6ak9, 6akh, 6p1m, 6p1n, 6p1o, 6p1p, 6p1q, 6p1r, 6p1s, 6p1t, 6p1u, 6p1v, 6p1w - hDpo μ residues 132-494+411-494 (mutant) + DNA + nucleotide derivative
    
  • 2ihm - mDpo μ catalytic domain + DNA – mouse
    
• DNA polymerase ν
  • 4xvi, 4xvk, 4xvl, 4xvm – hDpo ν catalytic domain + DNA
    
• DNA polymerase χ or repair DNA polymerase chi
  • 2m2t – AsfvDpo X – African swine fever virus – NMR
    
  • 2m2u, 2m2v – AsfvDpo X + nucleotide – NMR
    
  • 2m2w – AsfvDpo X + nucleotide + DNA – NMR
    
  • 5xma, 5xm9, 5xm8 – AsfvDpo X + DNA
    
  • 2w9m – DrDpo X
• DNA polymerase θ
  • 5a9j – hDpo helicase domain 1-894
    
  • 5a9f, 5aga – hDpo helicase domain + nucleotide
    
  • 4x0p, 4x0q – hDpo helicase domain + nucleotide + DNA
    
  • 6xbu – hDpo polymerase domain 1819-2590 + nucleotide + DNA
    
• DNA polymerase from yeast
  • 3oiq - yDpo α + cell division control protein 13
    
  • 3flo, 3lgb - yDpo α subunits A,B
    
  • 4b08, 4fvm - yDpo α subunit A
    
  • 4fxd, 4fyd - yDpo α subunit A + RNA + DNA
    
  • 5oki - yDpo α subunit A + DCC1 + chromosome fidelity protein
    
  • 3iay - yDpo δ catalytic subunit + DNA
    
  • 6p1h - yDpo δ catalytic+small+3 subunits + DNA + nucleotide – Cryo EM
    
  • 6wjv - yDpo II ε – Cryo EM
    
  • 6hv8 - yDpo II ε subunit A+B – Cryo EM
    
  • 3oha, 3ohb, 3mfh - yDpo ε (mutant) + DNA
    
  • 6i8a, 6qib - yDpo II ε subunit A + DNA + nucleotide 
    
  • 6g0a, 6fwk, 3mfi, 4m8o - yDpo II ε subunit A (mutant) + DNA + nucleotide derivative
    
  • 6s1c, 6s2e, 6s2f - yDpo II ε subunit A (mutant) + DCC1 + chromosome transmission fidelity proteins
    
  • 6i8a, 6qib - yDpo II ε subunit A + DNA + nucleotide 
    
  • 3mfi, 4m8o - yDpo ε (mutant) + DNA + nucleotide 
    
  • 6hv9 - yDpo II ε subunit A+B + CMG + DNA + nucleotide – Cryo EM
    
  • 2r8j, 2r8k, 4ptf - yDpo ε catalytic domain + DNA + nucleotide 
    
  • 6h1v - yDpo ε catalytic domain (mutant) + DNA + nucleotide 
    
  • 2xgp, 2xgq, 2wtf - yDpo ε + DNA
    
  • 7lxd - yDpo ζ catalytic+processivity subunits + hDpo d subunits 3+small – Cryo EM
    
  • 5y27, 5y26 - Dpo ε subunit D + transcription factor – fission yeast
    
  • 1jih, 5vtp – yDpo η catalytic domain
    
• DNA polymerase Rev1
  • 3gqc – hRev1 + DNA + nucleotide
    
  • 2ebw – hRev1 BRCT domain – NMR
    
  • 3bjy, 2aq4 – yRev1 catalytic domain + DNA + nucleotide
    
  • 2lsi - hDpo  peptide + hRev1
    
  • 4fjo, 4gk5 - hDpo  + hDpo  catalytic subunit + Rev1 + MAD2B
    
  • 2lsj, 2lsi - hDpo  + Rev1
    
  • 2lsk - mDpo  + Rev1
    
• Terminal deoxynucleotidyl transferase
  • 2coe – TdT BRCT domain – NMR
    
  • 1jms – mTdT catalytic domain + Mg
    
• Terminal deoxynucleotidyl transferase binary complex
  • 4iqt, 4iqu, 4iqv, 4iqw – mTdT catalytic domain + inhibitor
    
  • 4i2i – mTdT catalytic domain + Mg + Zn + adenosine-pentaphosphate
    
  • 4i2j – mTdT catalytic domain + CTP + Zn
    
  • 1kej – mTdT catalytic domain + ATP derivative + Co
    
  • 4i2d – mTdT catalytic domain + ATP derivative + Mg
    
  • 4i29 – mTdT catalytic domain + AMP derivative + Mn
    
  • 4i2b – mTdT catalytic domain + AMPCPP + Mg
    
  • 4i2c – mTdT catalytic domain + AMPCPP + Mn
    
  • 4i2a – mTdT catalytic domain + UMP derivative + Mg
    

Terminal deoxynucleotidyl transferase ternary complex with DNA

• • 4i2e – mTdT catalytic domain + AMPCPP + Co + DNA
    
  • 4i2h – mTdT catalytic domain + AMPCPP + Zn + Mg + DNA
    
  • 4i27 – mTdT catalytic domain + TTP derivative + TMP + Mg + DNA
    
  • 1kdh – mTdT catalytic domain + UMP derivative + Mg + DNA
    
  • 4i28, 4i2f – mTdT catalytic domain + Mg + Zn + DNA
    
  • 4i2g – mTdT catalytic domain + Mg + Co + DNA
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky, Joel L. Sussman