Cancer

The Progression of Cancer

Cancer is a class of diseases marked by uncontrolled cellular growth resulting in intrusion on and destruction of adjacent tissues, while often spreading to other locations in the body via the lymphatic or circulatory systems.

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Articles in Proteopedia concerning Cancer include:

• 8-Oxoguanine Glycosylase
• Antizyme Inhibitor
• Aromatase
• The levels of Arylamine N-acetyltransferase in the body has important consequences with regard to an individual’s susceptibility to certain drug-induced toxicities and cancer. Acetylation is a major route of biotransformation for many arylamines and hydrazine drugs and known carcinogens like cigarette smoke.
• Caspases
  • Caspase-6
  • Caspase-7 Dynamics
  • Caspase-9 Regulation
• Cisplatin Information
• Cyclin Dependent Kinase Inhibitor
• Cytochrome P450 Oxidoreductase
• DEBS
• Dihydrofolate Reductase, the Target of Methotrexate
• Estrogen receptor
• Forkhead box protein M1
• Growth Factors & Receptors
  • Growth Factors & Receptors
  • Autocrine motility factor
  • Bone morphogenetic protein
  • Colony-stimulating factor
  • Epidermal growth factor and Epidermal Growth Factor Receptor
  • Ephrin and Ephrin receptor
  • Fibroblast growth factor and Fibroblast growth factor receptor
  • Growth differentiation factor
  • Hepatocyte growth factor and Hepatocyte growth factor receptor
  • Insulin-like growth factor and Insulin-like growth factor receptor
    • IGF1
  • Interleukin
  • Platelet-derived growth factors and receptors
  • Tumor necrosis factor
    • Tumor necrosis factor receptor
    • Tumor necrosis factor ligand superfamily
  • Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor
• Heat Shock Protein 90
• Hypoxia Inducible Factor (HIF)
• Human 8-Oxoguanine Glycosylase Structure and Mechanism (HOGG1)
• Isocitrate dehydrogenase
• Kinases
  • Cyclin Dependent Kinase-4
  • Phosphoinositide 3-Kinases
  • Bcr-Abl_and_Imatinib_(STI571_or_Gleevec)
  • Receptor tyrosine kinases
  • Mitogen-Activated Proteins
    • Mitogen-activated protein kinase
    • Mitogen-activated protein kinase kinase
    • Mitogen-activated protein kinase kinase kinase
• Oncogenes
  • C-Myc - Proto-Oncogenic Gene
  • MDM2
  • P53 - Tumor Suppressing Gene
  • PTEN
  • SRC - Proto-Oncogenic Tyrosine Kinase Gene
• Proteins in Cancer
• The Ras Superfamily
• Retinoblastoma Protein
• Sonic Hedgehog
• Tamoxifen
• Taxol
  • Paclitaxel
  • Taxol Information
• Telomerase Reverse Transcriptase
• Thioredoxin Reductase
• Tumor-Necrosis Factor Apoptosis-Inducing Ligand
• YKL-40

To view Cancer related proteins which are Structure Index entries see:

• Endothelial Growth Factor Receptor
• Phosphoinositide 3-Kinase
• Vascular Endothelial Growth Factor
• Vascular Endothelial Growth Factor Receptor

To view automatically seeded indices concerning Cancer See:

• Anti-Cancer
• Cancer
• Cancer Therapeutic

To View FDA Approved Treatments for Cancer See: Treatments

To view other Proteopedia pages about diseases & drug targets, See: Pharmaceutical Drug Targets

Proteopedia Page Contributors and Editors (what is this?)

David Canner, Alexander Berchansky, Jaime Prilusky, Wayne Decatur, Gonzalo Garcia-Martin