User:Alexander Berchansky: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Eran Hodis (talk | contribs)
m Creating user page with biography of new user.
 
No edit summary
 
(199 intermediate revisions by the same user not shown)
Line 1: Line 1:
Alexander Berchansky, Israel Structural Proteomics Center, Weizmann Institute of Science
[[Image:1680.jpg|left|200px]]
 
Dr. Alexander Berchansky, Ph.D., Israel Structural Proteomics Center, Weizmann Institute of Science
 
{{Clear}}
'''My interesting pages:'''
*[[Acetylcholinesterase]]
*[[AChE inhibitors and substrates]]
*[[Mutations in BRCA1/BARD1 RING-domain heterodimer]]
*[[Mutations in Brca1 BRCT Domains]]
*[[Lactate Dehydrogenase]]
*[[Human Acetylcholinesterase]]
*[[Journal:Proteins:2|Missense Mutations in Phenylalanine Hydroxylase]]
*[[Ferredoxin]]
*[[Phosphofructokinase (PFK)]]
*[[Alcohol dehydrogenase]]
*[[Beta-glucosidase]]
*[[Aricept Complexed with Acetylcholinesterase (Hebrew)]]
*[[Aricept Complexed with Acetylcholinesterase (Russian)]]
*[[Prion]]
*[[Viral capsids]]
*[[Journal:Acta Cryst D:S2059798320011869|Lattice-translocation defects in some specific crystals of the catalytic head domain of influenza neuraminidase]], Linghui Li, Shuliu Dai, George F. Gao and Jiawei Wang [http://dx.doi.org/10.1107/S2059798320011869 http://dx.doi.org/10.1107/S2059798320011869]
*[[Proteins from Mycobacterium tuberculosis]]
*[[Treatment of Tuberculosis]]
*[[Iron–sulfur proteins]]
*[[Hemeproteins]]
*[[Neurotransmitters]]
*[[Growth factors]]
*[[Receptor]]
*[[Hormones and their receptors]]
 
'''CRISPR-Cas (under development):'''
*[[CRISPR-Cas|CRISPR-Cas Part I]]
*[[CRISPR-Cas Part II]]
*[[CRISPR-Cas9]]
 
'''Classification according to the Wikipedia page CRISPR [https://en.wikipedia.org/wiki/CRISPR] with additions'''
 
'''CRISPR Class 1 uses a complex of multiple Cas proteins'''
 
CRISPR type I (Cas3)
 
CRISPR type I-A (Cascade) - see [[CRISPR subtype I-A]]
 
CRISPR type I-B (Cascade) - see [[CRISPR subtype I-B]]
 
CRISPR type I-C (Cascade) - see [[CRISPR subtype I-C]]
 
CRISPR type I-D (Cas10d)
 
CRISPR type I-E (Cascade) - see [[CRISPR type I-E (Cascade)|CRISPR subtype I-E]]
 
CRISPR type I-F (Csy1, Csy2, Csy3) - see [[CRISPR subtype I-F]]
 
CRISPR type I-U (GSU0054)
 
CRISPR type III (Cas10)
 
CRISPR type III-A (Csm complex) - see [[CRISPR subtype III-A (Csm complex)]]
 
CRISPR type III-B (Cmr complex)
 
CRISPR type III-C (Cas10 or Csx11)
 
CRISPR type III-D (Csx10)
 
CRISPR type Orphan
 
CRISPR type IV (Csf1)
 
CRISPR type IV-A
 
CRISPR type IV-B
 
'''CRISPR Class 2 uses a single large Cas protein'''
 
CRISPR type II-A - see [[CRISPR-Cas9]]
 
CRISPR type II-B (Cas4)
 
CRISPR type II-C
 
CRISPR type V (Cpf1, C2c1, C2c3) - see [[CRISPR type V]]
 
CRISPR type VI (Cas13a (previously known as C2c2), Cas13b, Cas13c, Cas13d) - see [[CRISPR type VI]]
 
*[[Journal:Protein Science:3|''Torpedo californica'' acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif]]
*[[Journal:IUCrJ:S2052252521005340|X-ray crystallography studies of RoAb13 bound to PIYDIN, a part of the CCR5 N-terminal domain]]
*[[Journal:Acta Cryst F:S2053230X20016015|Using Yeast Surface Display to Engineer a Soluble and Crystallizable Construct of HPK1]]
*[[Journal:Acta Cryst D:S2059798320015004|The substrate binding in the bile acid transporter ASBT<sub>Yf</sub> of ''Yersinia frederiksenii'']]
*[[Journal:Acta Cryst D:S205979832001517X|An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter]]
*[[Journal:Acta Cryst D:S2059798321003922|Structure of the human factor VIIa/soluble tissue factor with calcium, magnesium and rubidium]]
*[[Journal:Angew Chem Int Ed:1|Fine tuning of chlorophyll spectra by protein-induced ring deformation]]
*[[Journal:JBIC:8|A hydrogen-bonding network formed by the B10-E7-E11 residues of a truncated hemoglobin from Tetrahymena pyriformis is critical for stability of bound oxygen and nitric oxide detoxification]]
*[[Journal:JBIC:12|ISC-like [2Fe-2S] ferredoxin (FdxB) dimer from ''Pseudomonas putida'' JCM 20004: Structural and electron nuclear double resonance characterization]]
*[[Journal:JBIC:13|{{nowrap|N-Butylisocyanide Oxidation}} at the {{nowrap|&#91;NiFe<sub>4</sub>S<sub>4</sub>OH<sub>x</sub>&#93;-cluster}} of CO Dehydrogenase]]
*[[Journal:JBIC:14|Multifaceted SlyD from ''Helicobacter pylori'': implication in [NiFe] hydrogenase maturation]]
*[[Journal:Acta Cryst D:S2059798320014540|Statistically correcting dynamical electron scattering improves refinement of protein nanocrystals, including charge refinement of coordinated metals]]
*[[Journal:JBIC:15|Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas proteolytica, by 8-Quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study]]
*[[Journal:JBIC:16|Laue Crystal Structure of ''Shewanella oneidensis'' Cytochrome c Nitrite Reductase from a High-yield Expression System]]
*[[Journal:JBIC:17|Peptidylglycine α-Hydroxylating Monooxygenase (PHM)-coordination of peroxide to Cu<sub>M</sub> center. Structural and computational study]]
*[[Journal:JBIC:18|Solution structure and dynamics of human S100A14]]
*[[Journal:JBIC:20|The crystal structure of ''Sporosarcina pasteurii'' urease in a complex with citrate provides new hints for inhibitor design]]
*[[Journal:JBIC:21|The mechanism of copper uptake by tyrosinase from ''Bacillus megaterium'']]
*[[Journal:JBIC:22|The crystal structure of an extracellular catechol oxidase from the ascomycete fungus <i>Aspergillus oryzae</i>]]
*[[Journal:JBIC:23|Selectivity of Ni(II) and Zn(II) binding to ''Sporosarcina pasteurii'' UreE, a metallo-chaperone in the urease assembly: a calorimetric and crystallographic study]]
*[[Journal:JBIC:24|Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain]]
*[[Journal:JBIC:25|Synthesis, characterization and binding properties towards CT-DNA and Lipoxygenase, of mixed ligand silver(I) complexes with 2-mercapto-thiazole and its derivatives and triphenylphosphine.]]
*[[Journal:JBIC:26|Fluoride inhibition of Sporosarcina pasteurii urease: structure and thermodynamics]]
*[[Journal:JBIC:27|Aromatic aldehydes at the active site of Aldehyde Oxidoreductase from Desulfovibrio gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interactions]]
*[[Journal:JBIC:28|Crystallographic studies of [NiFe]-hydrogenase mutants: towards consensus structures for the elusive unready oxidized states]]
*[[Journal:JBIC:29|High-resolution crystal structure of Z-DNA in complex with Cr3+ cations]]
*[[Journal:JBIC:30|Structural Characterization of Metal Binding to a Cold-adapted Frataxin]]
*[[Journal:JBIC:31|Conformational control of the binding of diatomic gases to cytochrome c’]]
*[[Journal:JBIC:32|Analyzing the Catalytic Role of Active Site Residues in the Fe-Type Nitrile Hydratase from ''Comamonas testosteroni'' Ni1]]
*[[Journal:JBIC:33|Structural characterization of zinc-bound Zmp1, a zinc-dependent metalloprotease secreted by Clostridium difficile]]
*[[Journal:FEBS Open Bio:2|Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands]]
*[[Journal:FLS:1|Crystal structure of porcine pancreatic phospholipase A<sub>2</sub> in complex with 2-methoxycyclohexa-2-5-diene-1,4-dione]]
*[[Journal:Genes:1|A DNA Structural Alphabet Distinguishes Structural Features of DNA Bound to Regulatory Proteins and in the Nucleosome Core Particle]]
*[[Journal:JBIC:7|Structural and kinetic studies of imidazole binding to two members of the cytochrome c6 family reveal an important role for a conserved heme pocket residue]]
*[[Journal:JBIC:9|Protein and metal cluster structure of the wheat metallothionein domain &gamma;-Ec-1. The second part of the puzzle.]]
*[[Journal:JBIC:11|{{nowrap|A Cryo-Crystallographic}} Time Course for Peroxide Reduction by Rubrerythrin from ''Pyrococcus furiosus'']]
*[[Journal:JMB:1|Cyt1Aa Toxin: High Resolution Structure Reveals Implications for its Membrane-Perforating Function]]
*[[Journal:JMB:3|Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme]]
*[[Journal:JMedChem:1|Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of SERMs]]
*[[Journal:JSB:1|Structural and functional insights into a dodecameric molecular machine – The RuvBL1/RuvBL2 complex]]
*[[Journal:Molecular Cell:1|Automated computational design of human enzymes for high bacterial expression and stability]]
*[[Journal:PLoS ONE:1|Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates]]
*[[Journal:PLoS ONE:2|Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4]]
*[[Journal:Protein Science:1|Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with ''Torpedo californica'' acetylcholinesterase]]
*[[Journal:Protein Science:2|The Impact of Crystallization Conditions on Structure-Based Drug Design: a Case Study on the Methylene Blue/Acetylcholinesterase Complex]]
*[[Journal:Science:1|Structural basis of transcription activation]]
*[[Journal:Structure:1|Promiscuous Protein Binding as a Function of Protein Stability]]
*[[Journal:JBSD:1|An Insight to the Dynamics of Conserved Water Mediated Salt Bridge Interaction and Inter-Domain Recognition in hIMPDH Isoforms]]
*[[Journal:JBSD:2|Elucidation by NMR solution of neurotensin in Small Unilamellar Vesicle environment: molecular surveys for neurotensin receptor recognition]]
*[[Journal:JBSD:4|Dominant-negative Effects in Prion Diseases: Insights from Molecular Dynamics Simulations on Mouse Prion Protein Chimeras]]
*[[Journal:JBSD:5|Influence of divalent magnesium ion on DNA: molecular dynamics simulation studies]]
*[[Journal:JBSD:6|Evidence-based docking of the urease activation complex]]
*[[Journal:JBSD:9|Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from ''Haemophilus ducreyi'': in silico and in vitro evidences]]
*[[Journal:JBSD:10|Para-(benzoyl)-phenylalanine as a potential inhibitor against LpxC of ''Leptospira spp.'': Homology modeling, docking and molecular dynamics study]]
*[[Journal:JBSD:11|Drug resistance mechanism of PncA in ''Mycobacterium Tuberculosis'']]
*[[Journal:JBSD:13|Mechanism of BAG1 repair on Parkinson’s disease-linked DJ1 mutation]]
*[[Journal:JBSD:14|Traditional Chinese medicine as dual guardians against hypertension and cancer?]]
*[[Journal:JBSD:15|The molecular origin of the MMR-dependent apoptosis pathway from dynamics analysis of MutSα-DNA complexes]]
*[[Journal:JBSD:16|The extracellular subunit interface of the 5-HT3 receptors: a computational alanine scanning mutagenesis study]]
*[[Journal:JBSD:17|DNA Conformation and Energy in Nucleosome Core: A Theoretical Approach]]
*[[Journal:JBSD:18|Molecular modeling study for conformational changes of Sirtuin 2 due to substrate and inhibitor binding]]
*[[Journal:JBSD:19|Crystal structure of the CN-hydrolase SA0302 from the pathogenic bacterium ''Staphylococcus aureus'' belonging to the Nit and NitFhit Branch of the nitrilase superfamily]]
*[[Journal:JBSD:20|Insight into TPMT*23 Mutation Mis-folding Using Molecular Dynamics Simulation and Protein Structure Analysis]]
*[[Journal:JBSD:21|Identification of structural motifs in the E2 glycoprotein of Chikungunya involved in virus - host interaction]]
*[[Journal:JBSD:22|Molecular dynamics simulations of the thermal stability of tteRBP and ecRBP]]
*[[Journal:JBSD:26|Investigation on the Site-Selective Binding of Bovine Serum Albumin by Erlotinib Hydrochloride]]
*[[Journal:JBSD:27|Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes]]
*[[Journal:JBSD:28|Investigation of Silent Information Regulator 1 (Sirt1) Agonists from Traditional Chinese Medicine]]
*[[Journal:JBSD:29|Han ethnicity-specific type 2 diabetic treatment from traditional Chinese medicine?]]
*[[Journal:JBSD:30|Conformational dynamics of full-length inducible human Hsp70 derived from microsecond molecular dynamics simulations in explicit solvent]]
*[[Journal:JBSD:31|Non-specificity and synergy at the binding site of the carboplatin-induced DNA adduct via molecular dynamics simulations of the MutSα-DNA recognition complex]]
*[[Journal:JBSD:35|A Possible Strategy against Head and Neck Cancer: ''In Silico''. Investigation of Three-in-One inhibitors]]
*[[Journal:JBSD:36|Structural Insights into the South African HIV-1 Subtype C Protease: Impact of hinge region dynamics and flap flexibility in drug resistance]]
*[[Journal:JBSD:38|Memory-Enhancement by Traditional Chinese Medicine?]]
*[[Journal:JBSD:39|The remarkable efficiency of a Pin-II proteinase inhibitor sans two conserved disulfide bonds is due to enhanced flexibility and hydrogen-bond density in the reactive loop]]
*[[Journal:JBSD:40|Traditional Chinese medicine application in HIV: An ''in silico'' study]]
*[[Journal:JBSD:41|Molecular Mechanism of HIV-1 gp120 Mutations That Reduce CD4 Binding Affinity]]
*[[Book:Structural Proteomics and its Impact on the Life Sciences:6]]‎
*[[Journal:Acta Cryst D:S0907444911047251|Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations]]
*[[Journal:Acta Cryst D:S2059798318000050|A DNA structural alphabet provides new insight into DNA flexibility]]
*[[Journal:Acta Cryst D:S2059798319000676|Crystal structures of pyrrolidone-carboxylate peptidase I from ''Deinococcus radiodurans'' reveal the mechanism of L-pyroglutamate recognition]]
*[[Journal:Acta Cryst D:S2059798318014900|Structure of the AmyC GH13 alpha-amylase from Alicyclobacillus sp, reveals accommodation of starch branching points in the alpha-amylase family]]
*[[Journal:Acta Cryst D:S2059798318017047|The crystal structure of the N-acetylglucosamine 2-epimerase from Nostoc sp. KVJ10 reveals the true dimer]]
*[[Journal:Acta Cryst D:S2059798318015322|Structure of ISG15 from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement]]
*[[Journal:Acta Cryst D:S2059798319000214|In-house high energy remote SAD-phasing using the magic triangle: how to tackle the P1 low symmetry using multiple orientations on the same human IBA57 crystal to increase multiplicity]]
*[[Journal:Acta Cryst D:S2059798319002912|Crystal structure of the pseudoenzyme PDX1.2 in complex with its cognate enzyme PDX1.3]]
*[[Journal:Acta Cryst D:S2059798319007113|Crystal Structure Determination of ''Pseudomonas stutzeri'' A1501 endoglucanase Cel5A]]
*[[Journal:Acta Cryst D:S2059798319006995|Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells]]
*[[Journal:Acta Cryst D:S2059798319002304|The third structural switch in the molecule of archaeal translation initiation factor 2 and its possible role in initiation of GTP hydrolysis and removal of aIF2 from the ribosome]]
*[[Journal:Acta Cryst D:S2059798319004169|Structural and functional insights into phosphomannose isomerase]]
*[[Journal:Acta Cryst F:S2053230X18016217|The structure of ''Mycobacterium tuberculosis'' HtrA reveals an auto-regulatory mechanism]]
*[[Journal:Acta Cryst F:S2053230X18014814|Crystal structure and kinetic analyses of a hexameric form of (S)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium acetobutylicum]]
*[[Journal:Acta Cryst F:S2053230X19000815|Crystal structure of Type VI immunity protein Tdi1 (Atu4351) from Agrobacterium tumefaciens]]
*[[Journal:Acta Cryst F:S2053230X19004151|Phasing with calcium at home]]
*[[Journal:Acta Cryst F:S2053230X19001213|Substrate analogue complex structure of ''Mycobacterium tuberculosis'' decaprenyl diphosphate synthase]]
*[[Journal:Acta Cryst F:S2053230X19004618|Novel T9 loop interaction of Filamenting Temperature-sensitive mutant Z from ''Mycobacterium tuberculosis'']]
*[[Journal:Acta Cryst F:S1744309112050270|Crystal structure of ADL1, a plant-specific homologue of the universal diaminopimelate amino transferase enzyme of lysine biosynthesis]]
*[[Journal:Acta Cryst F:S2053230X19002863|Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis]]
*[[Journal:Acta Cryst F:S2053230X19004424|Structure of the Ebola virus nucleoprotein - RNA complex]]
*[[Journal:Acta Cryst F:S1744309112003326|Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae]]
*[[Journal:Acta Cryst F:S2053230X18018083|An assessment of three human methylenetetrahydrofolate dehydrogenase/cyclohydrolase ligand complexes following further refinement]]
*[[Journal:Acta Cryst F:S2053230X19002693|Crystal structure of phosphoribulokinase from ''Synechococcus sp.'' strain PCC 6301]]
*[[Journal:Acta Cryst F:S1744309112003326|Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae]]
*[[Journal:Acta Cryst F:S2053230X19007192|Crystal Structure of Flavin Dependent Thymidylate Synthase, Thy1, from ''Thermus thermophilus'' having an Extra C Terminal Domain]]
*[[Journal:BMC:3|Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits]]
*[[Journal:FEBS Open Bio:2|Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands]]
*[[Journal:IUCrJ:S2052252519002926|Determination of the Molecular Basis for Coprogen Import by Gram Negative Bacteria]]
*[[Journal:IUCrJ:S2052252519001568|Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition]]
*[[Journal:IUCrJ:S2052252518018274|A cytosine modification mechanism revealed by the ternary complex structure of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate]]
*[[Journal:IUCrJ:S2052252519005372|The structural characterisation of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation]]
*[[Journal:IUCrJ:S2052252519005761|Room-temperature photo-induced martensitic transformation in a protein crystal]]
*[[SUMO]]
*[[EPSP synthase]]
*[[AMP-activated protein kinase]]
*[[Xanthine dehydrogenase]]
*[[Nicotinic Acetylcholine Receptor]]
*[[Cytochrome c]]
*[[Methotrexate]]
*[[Kemp elimination catalyst]]
*[[Urease]]
*[[Phosphoglycerate Kinase]]
*[[Plant-derived glucocerebrosidase]]
*[[NADH quinone oxidoreductase (NQO1) with inhibitor dicoumarol]]
*[[Matrix metalloproteinase]]
*[[Amino acid oxidase]]
*[[Mutant immunity protein 9 (variant R12-13)]]
*[[Acetylcholine binding protein]]
*[[Hydroxylase]]
*[[Actin]]
*[[Torpedo Californica Acetylcholinesterase in complex with an (R)-Tacrine-(10)-Hupyridone inhibitor]]
*[[Dronpa]]
*[[Major histocompatibility complex]]
*[[Mutant immunity protein 9 (variant R12-2)]]
*[[Butyrylcholinesterase]]
*[[Human acid-beta-glucosidase covalently bound to conduritol B epoxide]]
*[[Avidin]]
*[[Proteasome]]
*[[FK506 binding protein]]
*[[Insecticidal delta-endotoxin Cyt2Ba from Bacillus thuringiensis]]
*[[Ubiquitin protein ligase]]
*[[Catalase]]
*[[Albumin]]
*[[Aminopeptidase]]
*[[Staphylococcal nuclease]]
*[[Virus protease]]
*[[Asparaginase]]
*[[NAC transcription factor]]
*[[Kemp eliminase]]
*[[NADPH-Cytochrome P450 Reductase]]
*[[Prolyl hydroxylase domain]]
*[[Neuraminidase]]
*[[Carbonic anhydrase]]
*[[Carboxypeptidase]]
*[[ABC transporter]]
*[[Ubiquitin]]
*[[Cytochrome P450]]
*[[TEM1-beta-Lactamase/beta-lactamase Inhibitor Protein (BLIP)]]
*[[Acid beta-glucosidase with N-butyl-deoxynojirimycin]]
*[[Treatment of Gaucher disease]]
*[[Acyl carrier protein synthase]]
*[[Chimeras of alcohol dehydrogenases]]
*[[Dihydrodipicolinate synthase]]
*[[Directed evolution]]
*[[Colicin Immunity Protein]]
*[[Human FKBP52]]
*[[Opioid receptor]]
*[[Acetylcholine]]
*[[Heat Shock Proteins]]
*[[Dioxygenase]]
*[[Flavodoxin]]
*[[Phospholipase A2]]
*[[Tyrosine kinase]]
*[[Cellobiohydrolase]]
*[[Acid phosphatase]]
*[[Neuroglobin]]
*[[Hirudin]]
*[[GTP-binding protein]]
*[[Aldehyde dehydrogenase]]
*[[Delta-endotoxin]]
*[[Beta-lactamase]]
*[[Estrogen receptor]]
*[[DNA-binding protein VirE2 from Agrobacterium tumefaciens complexed with chaperone VirE1]]
*[[Alkaline phosphatase]]
*[[Cathepsin]]
*[[Prolyl Endopeptidase]]
*[[Forkhead box protein]]
*[[Subtilisin]]
*[[Hyaluronidase]]
*[[Lysine-specific histone demethylase]]
*[[Glycolate oxidase]]
*[[Chaperonin]]
*[[Nucleoprotein]]
*[[Transcriptional activator]]
*[[Chitinase]]
*[[Cluster of Differentiation CD38]]
*[[Tubulin]]
*[[SAM-dependent methyltransferase]]
*[[Lignin peroxidase]]
*[[Gyrase]]
*[[Methylesterase]]
*[[CAMP-dependent protein kinase]]
*[[Plasminogen]]
*[[Choline Oxidase]]
*[[Thioesterase]]
*[[Dopamine receptor]]
*[[Mitogen-activated protein kinase kinase]]
*[[Kinesin]]
*[[Gelsolin]]
*[[DNA glycosylase]]
*[[Mitogen-activated protein kinase]]
*[[Factor VIII]]
*[[BtuB]]
*[[BLUF domain protein]]
*[[Botulinum neurotoxin]]
*[[Blue copper oxidase CueO]]
*[[Beta-phosphoglucomutase]]
*[[Beta-ketoacyl-ACP reductase]]
*[[Beta-adrenergic receptor kinase]]
*[[Barnase]]
*[[Bacteriorhodopsin]]
*[[BA42]]
*[[Gramicidin]]
*[[Horseradish peroxidase]]
*[[Azurin]]
*[[Avirulence protein]]
*[[Autophagy-related protein]]
*[[ATP-citrate synthase]]
*[[Atlastin]]
*[[Catabolite gene activator protein]]
*[[Cytochrome bc1 complex]]
*[[Lactoferrin]]
*[[Glycosyltransferase]]
*[[Factor inhibiting HIF]]
*[[Ephrin receptor]]
*[[Aspartoacylase]]
*[[Aspartate carbamoyltransferase]]
*[[Proliferating Cell Nuclear Antigen]]
*[[Aspartate-semialdehyde dehydrogenase]]
*[[Ascorbate peroxidase]]
*[[Aromatic amine dehydrogenase]]
*[[Arginine kinase]]
*[[Antigen 85]]
*[[Anti-sigma factor antagonist]]
*[[Anthrax protective antigen]]
*[[Anthrax edema factor]]
*[[Annexin]]
*[[Aminotransferase]]
*[[Alpha-tubulin N-acetyltransferase]]
*[[Alpha-lytic protease]]
*[[Aldose Reductase]]
*[[Alanine racemase]]
*[[Agglutinin]]
*[[ADP-ribose pyrophosphatase]]
*[[Poly (ADP-ribose) polymerase]]
*[[Adenylosuccinate lyase]]
*[[Adenosine kinase]]
*[[Adenosine deaminase]]
*[[Adenosine A2A receptor]]
*[[Adaptin]]
*[[Acylaminoacyl peptidase]]
*[[Acyl carrier protein]]
*[[Acyl-CoA dehydrogenase]]
*[[Acetylxylan esterase]]
*[[Acetyl-CoA carboxylase]]
*[[Acetyl-CoA synthetase]]
*[[Acetyl-CoA synthase]]
*[[Cytochrome c oxidase]]
*[[Concanavalin A]]
*[[Neurexin]]
*[[Histone deacetylase]]
*[[Purine repressor]]
*[[Protein phosphatase]]
*[[Glutamate synthase]]
*[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase]]
*[[6-aminohexanoate-dimer hydrolase]]
*[[6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase]]
*[[7,8-dihydro-8-oxoguanine triphosphatase]]
*[[Cell division protein]]
*[[Carbon monoxide dehydrogenase]]
*[[CXC chemokine receptor]]
*[[Cyclin-dependent kinase]]
*[[12-oxophytodienoate reductase]]
*[[Enoyl-Acyl-Carrier Protein Reductase]]
*[[Dihydrolipoamide acetyltransferase]]
*[[Alpha-glucosidase]]
*[[Apoptotic protease-activating factor]]
*[[Arginase]]
*[[Adhesin]]
*[[Arabinanase]]
*[[Gp120]]
*[[GMP synthase]]
*[[Leukotriene A4 Hydrolase]]
*[[Biotin Protein Ligase]]
*[[Androgen receptor]]
*[[Glutamate dehydrogenase]]
*[[14-3-3 protein]]
*[[Fibrin]]
*[[3C protease]]
*[[GTPase KRas]]
*[[6-phosphogluconate dehydrogenase]]
*[[Mineralocorticoid receptor]]
*[[Thyroid hormone receptor]]
*[[Progesterone receptor]]
*[[Serpin]]
*[[Leucine transporter]]
*[[Microtubule-associated protein]]
*[[Ectonucleotide pyrophosphatase/phosphodiesterase]]
*[[Ribosome biogenesis protein]]
*[[Liver X receptor]]
*[[Nitrophorin]]
*[[VprBP]]
*[[Growth factor receptor-bound protein]]
*[[CREB-binding protein]]
*[[Kdo-8-phosphate synthase]]
*[[Signal recognition particle receptor]]
*[[Liver receptor homolog-1]]
*[[Orexin and Orexin receptor]]
*[[Spindlin]]
*[[Prostaglandin E synthase]]
*[[Terminase]]
*[[Mandelate racemase/muconate lactonizing enzyme]]
*[[GABA(A) receptor-associated protein]]
*[[IspG]]
*[[Haloperoxidase]]
*[[Cytochrome P450 hydroxylase]]
*[[Period circadian protein]]
*[[Proteinase]]
*[[Sialyltransferase]]
*[[Neprilysin]]
*[[Cholesterol esterase]]
*[[Chloramphenicol acetyltransferase]]
*[[Thiolase]]
*[[CCA-adding enzyme]]
*[[Glucose-fructose oxidoreductase]]
*[[Tripeptidyl peptidase]]
*[[Tryptophan synthase]]
*[[Fatty acid synthase]]
*[[Glucosamine 6-phosphate synthase]]
*[[Rho GTPase activating protein]]
*[[Ornithine decarboxylase]]
*[[Prostaglandin D synthase]]
*[[Prestin]]
*[[Polyamine oxidase]]
*[[Phosphotransferase]]
*[[Phosphodiesterase]]
*[[Plexin]]
*[[Plasminogen activator]]
*[[Plasmid segregation protein ParM]]
*[[Phospholipase C]]
*[[Phosphoenolpyruvate carboxylase]]
*[[Peptide N-glycanase]]
*[[Penicillopepsin]]
*[[Penicillin acylase]]
*[[PCSK9]]
*[[Galactose-binding lectin]]
*[[Paired box protein]]
*[[D-xylose isomerase]]
*[[Adrenodoxin reductase]]
*[[Methylamine dehydrogenase]]
*[[Oligopeptide-binding protein]]
*[[Met repressor]]
*[[Nuclear receptor coactivator]]
*[[Neuropilin]]
*[[NADH peroxidase]]
*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
*[[LDL receptor]]
*[[P63]]
*[[Galactose oxidase]]
*[[Leukotriene B4 hydroxydehydrogenase]]
*[[Leukocyte immunoglobulin-like receptor]]
*[[Alpha-lactalbumin]]
*[[3-phosphoinositide-dependent protein kinase 1]]
*[[2-isopropylmalate synthase]]
*[[Kelch-like protein]]
*[[Lactoperoxidase]]
*[[Mur ligase]]
*[[Calcineurin]]
*[[S100 protein]]
*[[Ecotin]]
*[[Leukotriene C4 synthase]]
*[[Jumonji domain-containing protein]]
*[[Monooxygenase]]
*[[Vanillyl-alcohol oxidase]]
*[[Isopropylmalate dehydrogenase]]
*[[Tumor necrosis factor]]
*[[Tumor necrosis factor receptor]]
*[[Mannosidase]]
*[[Transthyretin]]
*[[Transport inhibitor response 1]]
*[[Transducin]]
*[[Nitrate reductase]]
*[[Nitroreductase]]
*[[Dihydroorotate dehydrogenase]]
*[[L-rhamnose isomerase]]
*[[TRAIL]]
*[[Estrogen-related receptor]]
*[[Inosine monophosphate dehydrogenase]]
*[[Survivin]]
*[[UDP-N-acetylglucosamine acyltransferase]]
*[[Haptoglobin receptor]]
*[[D-alanine-D-alanine ligase]]
*[[Glutaminyl cyclase]]
*[[Severin]]
*[[Carnitine palmitoyltransferase]]
*[[Isoaspartyl dipeptidase]]
*[[Thiaminase]]
*[[Acetylcholinesterase with OTMA]]
*[[D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica]]
*[[Ferripyoverdine receptor]]
*[[Fatty acid-binding protein]]
*[[Rho-associated protein kinase]]
*[[Endonuclease]]
*[[Collagenase (non-MMP)]]
*[[Epoxidase]]
*[[Ferrochelatase]]
*[[Elastase]]
*[[Tyrosinase]]
*[[N-acetylornithine carbamoyltransferase]]
*[[Ornithine carbamoyltransferase]]
*[[Pantothenate kinase]]
*[[Pantothenate synthetase]]
*[[Parvalbumin]]
*[[Cephalosporin acylase]]
*[[Dipeptidyl peptidase]]
*[[Farnesyltransferase]]
*[[Farnesyl diphosphate synthase]]
*[[Arginine repressor]]
*[[Transferrin]]
*[[Transketolase]]
*[[Dihydropteroate synthase]]
*[[Trichodiene synthase]]
*[[DAHP synthase]]
*[[Trehalulose synthase]]
*[[TRNA-guanine transglycosylase]]
*[[Cyclophilin]]
*[[Cutinase]]
*[[Trypanothione reductase]]
*[[Trypsin inhibitor]]
*[[Tryptase]]
*[[Tubulin tyrosine ligase]]
*[[Transaldolase]]
*[[Urokinase]]
*[[Undecaprenyl pyrophosphate synthase]]
*[[UDP-galactose 4-epimerase]]
*[[Uridine 5'-monophosphate synthase]]
*[[Arsenate reductase]]
*[[Rac]]
*[[Rho GTPase]]
*[[Carbamoyl phosphate synthetase]]
*[[Dedicator of cytokinesis protein]]
*[[Phosphoribosylaminoimidazole carboxylase]]
*[[Retinoid isomerohydrolase]]
*[[Calcium uptake protein 1]]
*[[Abscisic acid receptor]]
*[[Apoptosis-inducing factor]]
*[[Nucleolin]]
*[[Aldo-keto reductase]]
*[[SAICAR synthetase]]
*[[Prolactin receptor]]
*[[Siderocalin]]
*[[Latrophilin]]
*[[Folypolyglutamate synthase]]
*[[WD repeat-containing protein]]
*[[Xylosidase]]
*[[Uridylate kinase]]
*[[Penicillin-binding protein]]
*[[Pentaerythritol tetranitrate reductase]]
*[[Thymidine kinase]]
*[[Thymidylate kinase]]
*[[Tissue factor pathway inhibitor]]
*[[Thioredoxin Reductase]]
*[[Peptidyl-tRNA hydrolase]]
*[[Peroxiredoxin]]
*[[Phenylethanolamine N-methyltransferase]]
*[[Tetracycline repressor protein]]
*[[Phenylpyruvate decarboxylase]]
*[[Succinate-semialdehyde dehydrogenase]]
*[[Spermidine/spermine N-acetyltransferase]]
*[[Sulfotransferase]]
*[[Phosphomannomutase]]
*[[Strictosidine Synthase]]
*[[Phosphoenolpyruvate carboxykinase]]
*[[Phosphoribosyltransferase]]
*[[Phosphoserine aminotransferase]]
*[[Phosphoserine phosphatase]]
*[[Shikimate kinase]]
*[[Shikimate dehydrogenase]]
*[[Selectin]]
*[[Selenocysteine synthase]]
*[[Semaphorin]]
*[[Serine palmitoyltransferase]]
*[[SAM decarboxylase]]
*[[SAM synthetase]]
*[[S-adenosylhomocysteine hydrolase]]
*[[Plasmepsin]]
*[[RNA uridylyltransferase]]
*[[Ribosomal protein S6 kinase]]
*[[Poly(A) RNA polymerase protein Cid1]]
*[[Ribonucleotide reductase]]
*[[Phycocyanobilin:ferredoxin oxidoreductase]]
*[[Poly (ADP-ribose) glycohydrolase]]
*[[Rhomboid protease]]
*[[Rhodopsin kinase]]
*[[Retinol-binding protein]]
*[[Polyneuridine Aldehyde Esterase]]
*[[Retinoid X receptor]]
*[[Porphobilinogen synthase]]
*[[Retinoblastoma-binding protein]]
*[[Pyruvate dehydrogenase kinase]]
*[[Pyruvate-ferredoxin oxidoreductase]]
*[[Pyrroline-5-carboxylate dehydrogenase]]
*[[Purine nucleoside phosphorylase]]
*[[Proline utilization A]]
*[[Protein kinase C]]
*[[Nucleoside diphosphate kinase]]
*[[Formate dehydrogenase]]
*[[NAD synthase]]
*[[Nuclear transcription factor Y]]
*[[Methanol dehydrogenase]]
*[[Matriptase]]
*[[Manganese peroxidase]]
*[[Mandelate racemase]]
*[[MEP cytidylyltransferase]]
*[[Mandelate dehydrogenase]]
*[[Malate synthase]]
*[[Macrophage inhibitory factor]]
*[[Homocitrate synthase]]
*[[Hemagglutinin-esterase]]
*[[Guanylate kinase]]
*[[Granzyme]]
*[[Glycosylasparaginase]]
*[[Glutaryl-CoA dehydrogenase]]
*[[Glutaminase]]
*[[Glutamate racemase]]
*[[Glucuronidase]]
*[[Glucose-1-phosphate thymidylyltransferase]]
*[[Geranylgeranyl transferase]]
*[[Galactose mutarotase]]
*[[Ficolin]]
*[[Phosphoinositide phosphatase]]
*[[Ferredoxin thioredoxin reductase]]
*[[PcrH]]
*[[Exportin]]
*[[Exoenzyme]]
*[[Epoxide hydrolase]]
*[[Elongation factor]]
*[[DNA damage-binding protein]]
*[[DNA adenine methylase]]
*[[Glucose 6-phosphate dehydrogenase]]
*[[Diphthine synthase]]
*[[Cytochrome f]]
*[[Cullin]]
*[[Cruzain]]
*[[Complement C3]]
*[[Formyl-CoA transferase]]
*[[Ferric hydroxamate uptake receptor]]
*[[Enoylpyruvate transferase]]
*[[Enoyl-CoA hydratase]]
*[[Cholesterol oxidase]]
*[[Ceruloplasmin]]
*[[Calpain]]
*[[DXP reductoisomerase]]
*[[Diphtheria toxin]]
*[[Diphtheria toxin repressor]]
*[[Diguanylate cyclase]]
*[[Dehydroquinase]]
*[[Dehaloperoxidase]]
*[[Death-associated protein kinase]]
*[[D-aminoacylase]]
*[[Cytochrome c peroxidase]]
*[[Cytochrome b5]]
*[[Cyclohydrolase]]
*[[Cocaine esterase]]
*[[CotA laccase]]
*[[Colicin I receptor]]
*[[Choline O-acetyltransferase]]
*[[Choline kinase]]
*[[5'-deoxy-5'-methylthioadenosine phosphorylase]]
*[[CD4]]
*[[Casein kinase]]
*[[Nitrile hydratase]]
*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
*[[Chitinase-3-like protein]]
*[[Insulin-like growth factor receptor]]
*[[Ribose-binding protein]]
*[[Nitrite reductase]]
*[[DNA methyltransferase]]
*[[Pre-mRNA-splicing factor]]
*[[Carboxylesterase]]
*[[Ankyrin]]
*[[Acetylcholinesterase with DFP]]
*[[IFG/DG-Cerezyme]]
*[[C-terminal portion of human eIF4GI]]
*[[Death Associated Protein 5]]
*[[Acetylcholinesterase complexed with N-9-(1',2',3',4'-tetrahydroacridinyl)-1,8-diaminooctane]]
*[[Torpedo californica acetylcholinesterase with alkylene-linked tacrine dimer (5 carbon linker)]]
*[[Thioredoxin Glutathione Reductase]]
*[[Journal:PMC:1]]

Latest revision as of 13:37, 20 July 2021

Dr. Alexander Berchansky, Ph.D., Israel Structural Proteomics Center, Weizmann Institute of Science

My interesting pages:

CRISPR-Cas (under development):

Classification according to the Wikipedia page CRISPR [1] with additions

CRISPR Class 1 uses a complex of multiple Cas proteins

CRISPR type I (Cas3)

CRISPR type I-A (Cascade) - see CRISPR subtype I-A

CRISPR type I-B (Cascade) - see CRISPR subtype I-B

CRISPR type I-C (Cascade) - see CRISPR subtype I-C

CRISPR type I-D (Cas10d)

CRISPR type I-E (Cascade) - see CRISPR subtype I-E

CRISPR type I-F (Csy1, Csy2, Csy3) - see CRISPR subtype I-F

CRISPR type I-U (GSU0054)

CRISPR type III (Cas10)

CRISPR type III-A (Csm complex) - see CRISPR subtype III-A (Csm complex)

CRISPR type III-B (Cmr complex)

CRISPR type III-C (Cas10 or Csx11)

CRISPR type III-D (Csx10)

CRISPR type Orphan

CRISPR type IV (Csf1)

CRISPR type IV-A

CRISPR type IV-B

CRISPR Class 2 uses a single large Cas protein

CRISPR type II-A - see CRISPR-Cas9

CRISPR type II-B (Cas4)

CRISPR type II-C

CRISPR type V (Cpf1, C2c1, C2c3) - see CRISPR type V

CRISPR type VI (Cas13a (previously known as C2c2), Cas13b, Cas13c, Cas13d) - see CRISPR type VI

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Eran Hodis